Suzanne M J Fleiszig
Overview
Explore the profile of Suzanne M J Fleiszig including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
78
Citations
1680
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Kumar N, Nieto V, Kroken A, Jedel E, Grosser M, Hallsten M, et al.
mBio
. 2022 Nov;
13(6):e0274222.
PMID: 36374039
Within epithelial cells, Pseudomonas aeruginosa depends on its type III secretion system (T3SS) to escape vacuoles and replicate rapidly in the cytosol. Previously, it was assumed that intracellular subpopulations remaining...
12.
Datta A, Lee J, Truong T, Evans D, Fleiszig S
Sci Rep
. 2022 Jun;
12(1):10655.
PMID: 35739166
Previously we reported contact lens-induced CD11c+ cell responses in healthy mouse corneas, a phenomenon that also occurs in humans. To test involvement of ocular-associated bacteria, the impact of topical antibiotics...
13.
Kroken A, Kumar N, Yahr T, Smith B, Nieto V, Horneman H, et al.
PLoS Pathog
. 2022 Feb;
18(2):e1010306.
PMID: 35130333
The Pseudomonas aeruginosa toxin ExoS, secreted by the type III secretion system (T3SS), supports intracellular persistence via its ADP-ribosyltransferase (ADPr) activity. For epithelial cells, this involves inhibiting vacuole acidification, promoting...
14.
Wan S, Datta A, Flandrin O, Metruccio M, Ma S, Nieto V, et al.
FASEB J
. 2021 Sep;
35(10):e21899.
PMID: 34569661
The cornea of the eye differs from other mucosal surfaces in that it lacks a viable bacterial microbiome and by its unusually high density of sensory nerve endings. Here, we...
15.
Tabor L, Grosser M, Metruccio M, Kumar N, Wu Y, Nieto V, et al.
Ocul Surf
. 2021 Jul;
22:94-102.
PMID: 34332149
Purpose: Previously, we showed that tear fluid protects corneal epithelial cells against Pseudomonas aeruginosa without suppressing bacterial viability. Here, we studied how tear fluid affects bacterial gene expression. Methods: RNA-sequencing...
16.
Nguyen N, Burnham C, Casadevall A, Estes M, Ferrell R, Fleiszig S
mBio
. 2021 May;
12(3):e0111621.
PMID: 34044593
Since early 2020, the world has witnessed the unprecedented accomplishments of the scientific community in the fight against the coronavirus disease 2019 (COVID-19) pandemic. In the meantime, we also learned...
17.
Wan S, Ma S, Evans D, Fleiszig S
PLoS One
. 2020 May;
15(5):e0234013.
PMID: 32470039
The healthy cornea is remarkably resistant to infection, quickly clearing deliberately inoculated bacteria such as Pseudomonas aeruginosa and Staphylococcus aureus. Contrasting with the adjacent conjunctiva and other body surfaces, it...
18.
Fleiszig S, Kroken A, Nieto V, Grosser M, Wan S, Metruccio M, et al.
Prog Retin Eye Res
. 2019 Nov;
76:100804.
PMID: 31756497
Contact lenses represent a widely utilized form of vision correction with more than 140 million wearers worldwide. Although generally well-tolerated, contact lenses can cause corneal infection (microbial keratitis), with an...
19.
Li J, Wan S, Metruccio M, Ma S, Nazmi K, Bikker F, et al.
Sci Rep
. 2019 Sep;
9(1):13146.
PMID: 31511582
The scavenging capacity of glycoprotein DMBT1 helps defend mucosal epithelia against microbes. DMBT1 binding to multiple bacterial species involves its conserved Scavenger Receptor Cysteine-Rich (SRCR) domains, localized to a 16-mer...
20.
Nieto V, Kroken A, Grosser M, Smith B, Metruccio M, Hagan P, et al.
mBio
. 2019 Aug;
10(4).
PMID: 31431558
is among bacterial pathogens capable of twitching motility, a form of surface-associated movement dependent on type IV pili (T4P). Previously, we showed that T4P and twitching were required for to...