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Sussan Nourshargh

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Articles 97
Citations 7592
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Recent Articles
1.
Kono Y, Pack C, Ichikawa T, Komatsubara A, Adam S, Miyazawa K, et al.
PNAS Nexus . 2024 Dec; 3(12):pgae527. PMID: 39677369
The nuclear lamina (NL) lines the nuclear envelope (NE) to maintain nuclear structure in metazoan cells. The major NL components, the nuclear lamins contribute to the protection against NE rupture...
2.
Reglero-Real N, Perez-Gutierrez L, Saleeb R, Nourshargh S, Collinson L, Yoshimura A
STAR Protoc . 2024 Sep; 5(3):103257. PMID: 39226173
Correlative light and electron microscopy (CLEM) greatly facilitate capturing the ultrastructure of spatially and/or temporally rare events. Here, we present a protocol for targeting regions of interests (ROIs) in tissue...
3.
Vestweber D, Claesson-Welsh L, McDonald D, Williams T, Schwartz M, Scallan J, et al.
Nat Cardiovasc Res . 2024 Aug; 2(12):1120-1124. PMID: 39196154
No abstract available.
4.
Rolas L, Stein M, Barkaway A, Reglero-Real N, Sciacca E, Yaseen M, et al.
EMBO Rep . 2024 Jun; 25(9):3842-3869. PMID: 38918502
Cellular senescence is a hallmark of advanced age and a major instigator of numerous inflammatory pathologies. While endothelial cell (EC) senescence is aligned with defective vascular functionality, its impact on...
5.
Benedicto I, Carmona R, Barettino A, Espinos-Estevez C, Gonzalo P, Nevado R, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(18):e2400752121. PMID: 38648484
Hutchinson-Gilford progeria syndrome (HGPS) is a rare disease caused by the expression of progerin, a mutant protein that accelerates aging and precipitates death. Given that atherosclerosis complications are the main...
6.
Vignarajah M, Wood A, Nelmes E, Subburayalu J, Herre J, Nourshargh S, et al.
J Leukoc Biol . 2024 Apr; 116(4):901-908. PMID: 38626309
Intercellular cell adhesion molecule 1 (ICAM-1) is a cell surface glycoprotein with a vital role in the immune response to pathogens. The expression pattern of ICAM-1 is wide ranging, encompassing...
7.
Cacho-Navas C, Lopez-Pujante C, Reglero-Real N, Colas-Algora N, Cuervo A, Conesa J, et al.
Elife . 2024 Apr; 12. PMID: 38597186
Epithelial intercellular adhesion molecule (ICAM)-1 is apically polarized, interacts with, and guides leukocytes across epithelial barriers. Polarized hepatic epithelia organize their apical membrane domain into bile canaliculi and ducts, which...
8.
Joulia R, Guerrero-Fonseca I, Girbl T, Coates J, Stein M, Vazquez-Martinez L, et al.
Nat Commun . 2022 Nov; 13(1):7029. PMID: 36396641
Neutrophil diapedesis is an immediate step following infections and injury and is driven by complex interactions between leukocytes and various components of the blood vessel wall. Here, we show that...
9.
Reglero-Real N, Perez-Gutierrez L, Nourshargh S
Autophagy . 2021 Nov; 17(12):4509-4511. PMID: 34720030
A defining feature of an inflammatory reaction is infiltration of neutrophils into tissues, a response that requires breaching of endothelial cells (ECs) that line the lumenal aspect of blood vessels....
10.
Sanchez-Lopez A, Espinos-Estevez C, Gonzalez-Gomez C, Gonzalo P, Andres-Manzano M, Fanjul V, et al.
Circulation . 2021 Oct; 144(22):1777-1794. PMID: 34694158
Background: Hutchinson-Gilford progeria syndrome (HGPS) is a rare disorder characterized by premature aging and death mainly because of myocardial infarction, stroke, or heart failure. The disease is provoked by progerin,...