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Beat A Imhof

Explore the profile of Beat A Imhof including associated specialties, affiliations and a list of published articles. Areas
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Articles 101
Citations 3445
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Recent Articles
1.
Stalin J, Coquoz O, Jeitziner Marcone R, Jemelin S, Desboeufs N, Delorenzi M, et al.
Biomedicines . 2023 Dec; 11(12). PMID: 38137406
The melanoma cell adhesion molecule, shed from endothelial and cancer cells, is a soluble growth factor that induces tumor angiogenesis and growth. However, the molecular mechanism accounting for its generation...
2.
von Werdt D, Gungor B, Barreto de Albuquerque J, Gruber T, Zysset D, Kwong Chung C, et al.
Front Immunol . 2023 May; 14:1085895. PMID: 37153600
Members of the Regulator of G-protein signaling (Rgs) family regulate the extent and timing of G protein signaling by increasing the GTPase activity of Gα protein subunits. The Rgs family...
3.
Iftakhar-E-Khuda I, Pessia A, Zheng S, Kankainen M, Kontro M, Karikoski M, et al.
Cell Mol Life Sci . 2021 Nov; 78(23):7851-7872. PMID: 34719737
Although the development of hematopoietic stem cells (HSC) has been studied in great detail, their heterogeneity and relationships to different cell lineages remain incompletely understood. Moreover, the role of Vascular...
4.
Stalin J, Imhof B, Coquoz O, Jeitziner R, Hammel P, McKee T, et al.
Cancers (Basel) . 2021 Sep; 13(18). PMID: 34572851
The role of the proangiogenic factor olfactomedin-like 3 (OLFML3) in cancer is unclear. To characterize OLFML3 expression in human cancer and its role during tumor development, we undertook tissue expression...
5.
Blum E, Margalit R, Levy L, Getter T, Lahav R, Zilber S, et al.
Molecules . 2021 Aug; 26(15). PMID: 34361736
We recently developed a molecule (GT-73) that blocked leukocyte transendothelial migration from blood to the peripheral tissues, supposedly by affecting the platelet endothelial cell adhesion molecule (PECAM-1) function. GT-73 was...
6.
Imhof B, Ballet R, Hammel P, Jemelin S, Garrido-Urbani S, Ikeya M, et al.
FASEB J . 2020 Sep; 34(11):15559-15576. PMID: 32997357
Pericytes promote vessel stability and their dysfunction causes pathologies due to blood vessel leakage. Previously, we reported that Olfactomedin-like 3 (Olfml3) is a matricellular protein with proangiogenic properties. Here, we...
7.
Eichin D, Pessia A, Takeda A, Laakkonen J, Bellmann L, Kankainen M, et al.
Eur J Immunol . 2020 Sep; 51(1):231-246. PMID: 32970335
CD73 is an important ectoenzyme responsible for the production of extracellular adenosine. It is involved in regulating inflammatory responses and cell migration and is overexpressed in various cancers. The functions...
8.
Uckay I, Imhof B, Kressmann B, Lew D, Lipsky B, Sidibe A
Stem Cells Dev . 2020 May; 29(14):911-918. PMID: 32423362
Many persons with diabetes mellitus have limb ischemia, which is a major clinical problem. A subset of human monocytes that expresses TIE-2 may enhance neovascularization. We performed 179 phlebotomies on...
9.
Molica F, Meens M, Pelli G, Hautefort A, Emre Y, Imhof B, et al.
Thromb Res . 2019 Nov; 183:56-62. PMID: 31669824
Background: Hemostasis is a tightly regulated physiological process to rapidly induce hemostatic plugs at sites of vascular injury. Inappropriate activation of this process may lead to thrombosis, i.e. pathological blood...
10.
Roch A, Magon N, Maire J, Suarna C, Ayer A, Waldvogel S, et al.
JCI Insight . 2019 Oct; 4(21). PMID: 31581149
The RBC storage lesion is a multiparametric response that occurs during storage at 4°C, but its impact on transfused patients remains unclear. In studies of the RBC storage lesion, the...