Susanne Walz
Overview
Explore the profile of Susanne Walz including associated specialties, affiliations and a list of published articles.
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23
Citations
1856
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Recent Articles
1.
Wiegering A, Uthe F, Jamieson T, Ruoss Y, Huttenrauch M, Kuspert M, et al.
Cancer Discov
. 2025 Mar;
15(3):656.
PMID: 40025952
No abstract available.
2.
Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemia
Garitano-Trojaola A, Sancho A, Gotz R, Eiring P, Walz S, Jetani H, et al.
Commun Biol
. 2021 Jun;
4(1):799.
PMID: 34172833
The presence of FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) is one of the most frequent mutations in acute myeloid leukemia (AML) and is associated with an unfavorable prognosis. FLT3...
3.
Cossa G, Roeschert I, Prinz F, Baluapuri A, Vidal R, Schulein-Volk C, et al.
Mol Cell
. 2021 Jun;
81(11):2495.
PMID: 34087181
No abstract available.
4.
Peixoto J, Janaki-Raman S, Schlicker L, Schmitz W, Walz S, Winkelkotte A, et al.
Cancers (Basel)
. 2021 Apr;
13(6).
PMID: 33809510
Altered metabolic processes contribute to carcinogenesis by modulating proliferation, survival and differentiation. Tumours are composed of different cell populations, with cancer stem-like cells being one of the most prominent examples....
5.
Poon E, Liang T, Jamin Y, Walz S, Kwok C, Hakkert A, et al.
J Clin Invest
. 2020 Oct;
130(11):5875-5892.
PMID: 33016930
The undruggable nature of oncogenic Myc transcription factors poses a therapeutic challenge in neuroblastoma, a pediatric cancer in which MYCN amplification is strongly associated with unfavorable outcome. Here, we show...
6.
Grundl M, Walz S, Hauf L, Schwab M, Werner K, Spahr S, et al.
PLoS Genet
. 2020 May;
16(5):e1008818.
PMID: 32469866
The Hippo signalling pathway and its central effector YAP regulate proliferation of cardiomyocytes and growth of the heart. Using genetic models in mice we show that the increased proliferation of...
7.
Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Fischer T, Walz S, et al.
EMBO Mol Med
. 2020 Mar;
12(4):e11101.
PMID: 32128997
The transcription factor ∆Np63 is a master regulator of epithelial cell identity and essential for the survival of squamous cell carcinoma (SCC) of lung, head and neck, oesophagus, cervix and...
8.
Cossa G, Roeschert I, Prinz F, Baluapuri A, Vidal R, Schulein-Volk C, et al.
Mol Cell
. 2020 Feb;
77(6):1322-1339.e11.
PMID: 32006464
Deregulated expression of MYC induces a dependence on the NUAK1 kinase, but the molecular mechanisms underlying this dependence have not been fully clarified. Here, we show that NUAK1 is a...
9.
Kaymak I, Maier C, Schmitz W, Campbell A, Dankworth B, Ade C, et al.
Cancer Res
. 2019 Nov;
80(2):189-203.
PMID: 31744820
Oncogene activation and loss of tumor suppressor function changes the metabolic activity of cancer cells to drive unrestricted proliferation. Moreover, cancer cells adapt their metabolism to sustain growth and survival...
10.
Schmidt S, Gay D, Uthe F, Denk S, Paauwe M, Matthes N, et al.
Nat Cell Biol
. 2019 Nov;
21(11):1413-1424.
PMID: 31685988
Tumours depend on altered rates of protein synthesis for growth and survival, which suggests that mechanisms controlling mRNA translation may be exploitable for therapy. Here, we show that loss of...