Susan Marqusee
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Explore the profile of Susan Marqusee including associated specialties, affiliations and a list of published articles.
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99
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2418
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Recent Articles
1.
Shoemaker S, Luo M, Dam K, Pak J, Hoffmann M, Marqusee S
bioRxiv
. 2025 Feb;
PMID: 39975226
We report a detailed analysis of the full-length SARS-CoV-2 spike dynamics within a native-like membrane environment and variants inaccessible to studies on soluble constructs by conducting hydrogen-deuterium exchange mass spectrometry...
2.
Volz S, Malone J, Guseman A, Gronenborn A, Marqusee S
Proc Natl Acad Sci U S A
. 2025 Feb;
122(6):e2410860122.
PMID: 39899721
Human γD-crystallin, a monomeric protein abundant in the eye lens nucleus, must remain stably folded for an individual's entire lifetime to avoid aggregation and protein deposition-associated cataract formation. γD-crystallin contains...
3.
Gupta S, Russell B, Kristensen L, Tyler J, Costello S, Marqusee S, et al.
Anal Methods
. 2025 Jan;
17(6):1214-1225.
PMID: 39749913
X-ray footprinting mass spectrometry (XFMS) is a structural biology method that uses broadband X-rays for hydroxyl radical labeling to map protein interactions and conformation in solution. However, while XFMS alone...
4.
Hood M, Marqusee S
bioRxiv
. 2024 Sep;
PMID: 39314365
A protein's energy landscape, all accessible conformations, their populations, and dynamics of interconversion, is encoded in its primary sequence. While how a protein's primary sequence encodes its native state is...
5.
Dall N, Mendonca C, Torres Vera H, Marqusee S
Proc Natl Acad Sci U S A
. 2024 Aug;
121(34):e2321999121.
PMID: 39145938
Protein folding in the cell often begins during translation. Many proteins fold more efficiently cotranslationally than when refolding from a denatured state. Changing the vectorial synthesis of the polypeptide chain...
6.
Arkinson C, Dong K, Gee C, Costello S, Marqusee S, Martin A
bioRxiv
. 2024 Jun;
PMID: 38915702
The ubiquitin-like modifier FAT10 targets hundreds of proteins in the mammalian immune system to the 26S proteasome for degradation. This degradation pathway requires the cofactor Nub1, yet the underlying mechanisms...
7.
Nixon C, Lim S, Sternke M, Barrick D, Harms M, Marqusee S
Protein Sci
. 2024 May;
33(6):e5011.
PMID: 38747388
A protein sequence encodes its energy landscape-all the accessible conformations, energetics, and dynamics. The evolutionary relationship between sequence and landscape can be probed phylogenetically by compiling a multiple sequence alignment...
8.
Kumar K, Wang H, Habrian C, Latorraca N, Xu J, OBrien E, et al.
Nature
. 2024 May;
629(8013):E13.
PMID: 38702522
No abstract available.
9.
Kumar K, Wang H, Habrian C, Latorraca N, Xu J, OBrien E, et al.
Nature
. 2024 Apr;
629(8013):951-956.
PMID: 38632403
Metabotropic glutamate receptors belong to a family of G protein-coupled receptors that are obligate dimers and possess a large extracellular ligand-binding domain that is linked via a cysteine-rich domain to...
10.
Latorraca N, Sabaat S, Habrian C, Bleier J, Stanley C, Marqusee S, et al.
bioRxiv
. 2024 Mar;
PMID: 38464305
The G protein-coupled metabotropic glutamate receptors form homodimers and heterodimers with highly diverse responses to glutamate and varying physiological function. The molecular basis for this diversity remains poorly delineated. We...