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» Authors » Sunitha Rani Routhu

Sunitha Rani Routhu

Explore the profile of Sunitha Rani Routhu including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 32
Followers 0
Related Specialties
Chemistry
Biochemistry
Top 10 Co-Authors
Ahmed Kamal
C Ganesh Kumar
Srinivasa Reddy Bonam
Bathini Nagendra Babu
Anver Basha Shaik
Faria Sultana
M Sampath Kumar Halmuthur
V Ganga Reddy
V Lakshma Nayak
Ravikumar Akunuri
Published In
Bioorg Chem
Org Biomol Chem
Bioorg Med Chem
Eur J Med Chem
RSC Med Chem
Affiliations
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Recent Articles
1.
Identification, characterization and evaluation of novel antifungal cyclic peptides from Neobacillus drentensis
Routhu S, Ragi N, Yedla P, Shaik A, Venkataraman G, Cheemalamarri C, et al.
Bioorg Chem . 2021 Jul; 115:105180. PMID: 34332234
Marine microbes secrete exopolymeric substances (EPS), which surrounds the biofilm and inhibits the fungal growth. Elucidation of the structure and function of the extracellular exopolymeric substances is of vital relevance...
2.
New imidazo[2,1-]thiazole-based aryl hydrazones: unravelling their synthesis and antiproliferative and apoptosis-inducing potential
Shareef M, Devi G, Routhu S, Kumar C, Kamal A, Babu B
RSC Med Chem . 2021 Jan; 11(10):1178-1184. PMID: 33479622
Herein, we have designed and synthesized new imidazo[2,1-]thiazole-based aryl hydrazones () and evaluated their anti-proliferative potential against a panel of human cancer cell lines. Among the synthesized compounds, and elicited...
3.
Corrigendum to "Synthesis of benzo[d]imidazo[2,1-b]thiazole-chalcone conjugates as microtubule targeting and apoptosis inducing agents" [Bioorg. Chem. 76 (2018) 1-12]
Sultana F, Bonam S, Reddy V, Nayak V, Akunuri R, Routhu S, et al.
Bioorg Chem . 2020 Feb; 96:103070. PMID: 32062062
No abstract available.
4.
Synthesis and biological evaluation of pyrazole linked benzothiazole-β-naphthol derivatives as topoisomerase I inhibitors with DNA binding ability
Nagaraju B, Kovvuri J, Kumar C, Routhu S, Shareef M, Kadagathur M, et al.
Bioorg Med Chem . 2019 Jan; 27(5):708-720. PMID: 30679134
A series of new pyrazole linked benzothiazole-β-naphthol derivatives were designed and synthesized using a simple, efficient and ecofriendly route under catalyst-free conditions in good to excellent yields. These derivatives were...
5.
Synthesis of benzo[d]imidazo[2,1-b]thiazole-chalcone conjugates as microtubule targeting and apoptosis inducing agents
Sultana F, Bonam S, Reddy V, Nayak V, Akunuri R, Routhu S, et al.
Bioorg Chem . 2017 Nov; 76:1-12. PMID: 29102724
A series of benzo[d]imidazo[2,1-b]thiazole-chalcone conjugates (5a-aa) were designed, synthesized and evaluated for their cytotoxic potency against a panel of human cancer cell lines like lung (A-549), breast (MDA MB-231), prostrate...
6.
Design, synthesis and biological evaluation of novel pyrazolochalcones as potential modulators of PI3K/Akt/mTOR pathway and inducers of apoptosis in breast cancer cells
Shaik A, Rao G, Kumar G, Patel N, Reddy V, Khan I, et al.
Eur J Med Chem . 2017 Aug; 139:305-324. PMID: 28803046
Cancer has been established as the "Emperor of all maladies". In recent years, medicinal chemistry has focused on identifying novel anti-cancer compounds; though discovery of these compounds appears to be...
7.
Synthesis, DNA binding affinity and anticancer activity of novel 4H-benzo[g][1,2,3]triazolo[5,1-c][1,4]oxazocines
Visweswara Sastry K, Routhu S, Datta S, Nagesh N, Babu B, Nanubolu J, et al.
Org Biomol Chem . 2016 Oct; 14(39):9294-9305. PMID: 27714202
A new class of tricyclic heterocycles 4H-benzo[g][1,2,3]triazolo[5,1-c][1,4]oxazocines was synthesized through a Knoevenagel condensation/azide-alkyne cycloaddition reaction cascade in one-pot operation. These eight membered ring containing heterocycles exhibited moderately high anticancer activity...