Sunish Mohanan
Overview
Explore the profile of Sunish Mohanan including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
832
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0
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Recent Articles
1.
Siso S, Kavirayani A, Couto S, Stierstorfer B, Mohanan S, Morel C, et al.
Toxicol Pathol
. 2024 Dec;
53(1):5-20.
PMID: 39673215
Pathology, a fundamental discipline that bridges basic scientific discovery to the clinic, is integral to successful drug development. Intrinsically multimodal and multidimensional, anatomic pathology continues to be empowered by advancements...
2.
Papenfuss T, Himmel L, Kuper C, Mohanan S, Harleman J, Elmore S
Toxicol Pathol
. 2023 Aug;
51(4):205-215.
PMID: 37578155
The evaluation of changes in the immune system serves to determine the efficacy and potential immunotoxicologic effects of new products under development. Toxicologic pathologists play critical roles in identifying immune...
3.
Yang J, Jiao J, Draheim K, Yang G, Yang H, Yao L, et al.
FASEB J
. 2023 May;
37(6):e22995.
PMID: 37219526
Immuno-oncology (IO)-based therapies such as checkpoint inhibitors, bi-specific antibodies, and CAR-T-cell therapies have shown significant success in the treatment of several cancer indications. However, these therapies can result in the...
4.
Alsaid H, Cheng S, Bi M, Xie F, Rambo M, Skedzielewski T, et al.
Mol Imaging Biol
. 2022 Oct;
25(3):528-540.
PMID: 36266600
Purpose: The presence and functional competence of intratumoral CD8 T cells is often a barometer for successful immunotherapeutic responses in cancer. Despite this understanding and the extensive number of clinical-stage...
5.
He F, Springer N, Whitman M, Pathi S, Lee Y, Mohanan S, et al.
Biomaterials
. 2019 Sep;
224:119489.
PMID: 31546097
While ductal carcinoma in situ (DCIS) is known as a precursor lesion to most invasive breast carcinomas, the mechanisms underlying this transition remain enigmatic. DCIS is typically diagnosed by the...
6.
Mohanan S, Maguire S, Klapwijk J, Adler R, Haworth R, Clements P
Toxicol Pathol
. 2019 Jan;
47(2):121-128.
PMID: 30651043
GlaxoSmithKline has recently made significant organizational changes to its nonclinical safety, drug metabolism and pharmacokinetic, and laboratory animal science/veterinary functions, with the goal to increase our focus on scientific partnership...
7.
Mohanan S, Horibata S, Anguish L, Mukai C, Sams K, McElwee J, et al.
Cell Tissue Res
. 2017 Aug;
370(2):275-283.
PMID: 28766045
We previously found that transgenic mice overexpressing MMTV-FLAG-hPAD2 (PAD2OE) developed spontaneous skin lesions, with a subset of these lesions progressing to invasive squamous cell carcinoma (SCC). The goal of this...
8.
Seo B, Bhardwaj P, Choi S, Gonzalez J, Andresen Eguiluz R, Wang K, et al.
Sci Transl Med
. 2015 Aug;
7(301):301ra130.
PMID: 26290412
Obesity and extracellular matrix (ECM) density are considered independent risk and prognostic factors for breast cancer. Whether they are functionally linked is uncertain. We investigated the hypothesis that obesity enhances...
9.
McElwee J, Mohanan S, Horibata S, Sams K, Anguish L, McLean D, et al.
Cancer Res
. 2014 Sep;
74(21):6306-17.
PMID: 25213324
Peptidylarginine deiminase 2 (PAD2/PADI2) has been implicated in various inflammatory diseases and, more recently, cancer. The goal of this study was to test the hypothesis that PAD2 promotes oncogenesis using...
10.
Infanger D, Cho Y, Lopez B, Mohanan S, Liu S, Gursel D, et al.
Cancer Res
. 2013 Oct;
73(23):7079-89.
PMID: 24121485
Glioblastoma multiforme contains a subpopulation of cancer stem-like cells (CSC) believed to underlie tumorigenesis and therapeutic resistance. Recent studies have localized CSCs in this disease adjacent to endothelial cells (EC)...