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Sunando Roy

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Articles 56
Citations 704
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Recent Articles
1.
Buddle S, Forrest L, Akinsuyi N, Martin Bernal L, Brooks T, Venturini C, et al.
Genome Med . 2024 Sep; 16(1):111. PMID: 39252069
Background: Metagenomics is a powerful approach for the detection of unknown and novel pathogens. Workflows based on Illumina short-read sequencing are becoming established in diagnostic laboratories. However, high sequencing depth...
2.
Woodall M, Cujba A, Worlock K, Case K, Masonou T, Yoshida M, et al.
Nat Microbiol . 2024 Jun; 9(11):3076. PMID: 38890492
No abstract available.
3.
Woodall M, Cujba A, Worlock K, Case K, Masonou T, Yoshida M, et al.
Nat Microbiol . 2024 Apr; 9(5):1293-1311. PMID: 38622380
Children infected with SARS-CoV-2 rarely progress to respiratory failure. However, the risk of mortality in infected people over 85 years of age remains high. Here we investigate differences in the...
4.
Illingworth C, Guerra-Assuncao J, Gregg S, Charles O, Pang J, Roy S, et al.
Virus Evol . 2024 Mar; 10(1):veae001. PMID: 38486802
Mutagenic antiviral drugs have shown promise against multiple viruses, but concerns have been raised about whether their use might promote the emergence of new and harmful viral variants. Recently, genetic...
5.
Standing J, Buggiotti L, Guerra-Assuncao J, Woodall M, Ellis S, Agyeman A, et al.
Nat Commun . 2024 Feb; 15(1):1652. PMID: 38396069
Viral clearance, antibody response and the mutagenic effect of molnupiravir has not been elucidated in at-risk populations. Non-hospitalised participants within 5 days of SARS-CoV-2 symptoms randomised to receive molnupiravir (n ...
6.
Kreins A, Roux E, Pang J, Cheng I, Charles O, Roy S, et al.
Clin Immunol . 2024 Jan; 259:109901. PMID: 38218209
Chronic human norovirus (HuNoV) infections in immunocompromised patients result in severe disease, yet approved antivirals are lacking. RNA-dependent RNA polymerase (RdRp) inhibitors inducing viral mutagenesis display broad-spectrum in vitro antiviral...
7.
Chhabra P, Tully D, Mans J, Niendorf S, Barclay L, Cannon J, et al.
Emerg Infect Dis . 2023 Dec; 30(1):163-167. PMID: 38063078
We detected a novel GII.4 variant with an amino acid insertion at the start of epitope A in viral protein 1 of noroviruses from the United States, Gabon, South Africa,...
8.
Ortiz A, Kendall M, Storey N, Hatcher J, Dunn H, Roy S, et al.
Elife . 2023 Sep; 12. PMID: 37732733
Accurate inference of who infected whom in an infectious disease outbreak is critical for the delivery of effective infection prevention and control. The increased resolution of pathogen whole-genome sequencing has...
9.
Gil E, Roy S, Best T, Hatcher J, Breuer J
J Clin Virol . 2023 Aug; 166:105555. PMID: 37536014
Background: Rhinovirus (HRV) is a significant seasonal pathogen in children. The emergence of SARS-CoV2, and the social restrictions introduced in, disrupted viral epidemiology. Here we describe the experience of Great...
10.
Morfopoulou S, Buddle S, Torres Montaguth O, Atkinson L, Guerra-Assuncao J, Moradi Marjaneh M, et al.
Nature . 2023 Mar; 617(7961):564-573. PMID: 36996872
Since its first identification in Scotland, over 1,000 cases of unexplained paediatric hepatitis in children have been reported worldwide, including 278 cases in the UK. Here we report an investigation...