Sunali Mehta
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Explore the profile of Sunali Mehta including associated specialties, affiliations and a list of published articles.
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29
Citations
429
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Recent Articles
1.
Ray Das S, Delahunt B, Lasham A, Li K, Wright D, Print C, et al.
Pathology
. 2024 Apr;
56(4):473-483.
PMID: 38594116
The clinical importance of assessing and combining data on TP53 mutations and isoforms is discussed in this article. It gives a succinct overview of the structural makeup and key biological...
2.
Wiles A, Mehta S, Millier M, Woolley A, Li K, Parker K, et al.
Arthritis Res Ther
. 2023 Apr;
25(1):62.
PMID: 37060003
Background: The p53 isoform Δ133p53β is known to be associated with cancers driven by inflammation. Many of the features associated with the development of inflammation in rheumatoid arthritis (RA) parallel...
3.
Jesus A, Taha A, Wang D, Mehta P, Mehta S, Reily-Bell A, et al.
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674782
The Δ133p53β isoform is increased in many primary tumors and has many tumor-promoting properties that contribute to increased proliferation, migration and inflammation. Here we investigated whether Δ133p53β contributed to some...
4.
Mehta S, Wright D, Black M, Merrie A, Anjomshoaa A, Munro F, et al.
JNCI Cancer Spectr
. 2022 Oct;
6(6).
PMID: 36255250
Genomic analysis of tumors is transforming our understanding of cancer. However, although a great deal of attention is paid to the accuracy of the cancer genomic data itself, less attention...
5.
Shields N, Peyroux E, Campbell K, Mehta S, Woolley A, Counoupas C, et al.
J Immunol
. 2022 Sep;
209(9):1635-1651.
PMID: 36104111
The initiation of CD8 T cell responses against dead cell-associated Ags is tightly regulated, facilitating adaptive immunity against pathogens and tumors while preventing autoimmunity. It is now well established that...
6.
Li K, Ly K, Mehta S, Braithwaite A
Clin Transl Immunology
. 2022 May;
11(5):e1394.
PMID: 35620584
The principal function of inflammation is cellular defence against 'danger signals' such as tissue injury and pathogen infection to maintain the homeostasis of the organism. The initiation and progression of...
7.
Nezbedova L, McGhie T, Christensen M, Heyes J, Nasef N, Mehta S
Nutrients
. 2021 Nov;
13(11).
PMID: 34836282
Cancer is one of the leading causes of death globally. Epidemiological studies have strongly linked a diet high in fruits to a lower incidence of cancer. Furthermore, extensive research shows...
8.
Mehta S, Campbell H, Drummond C, Li K, Murray K, Slatter T, et al.
EMBO Rep
. 2021 Nov;
22(12):e53085.
PMID: 34779563
All living organisms have developed processes to sense and address environmental changes to maintain a stable internal state (homeostasis). When activated, the p53 tumour suppressor maintains cell and organ integrity...
9.
McDougall L, Kueh J, Ward J, Tyndall J, Woolley A, Mehta S, et al.
Front Oncol
. 2021 Nov;
11:709540.
PMID: 34722257
Colorectal cancer is primarily a disease of the developed world. The incidence rate has continued to increase over time, reflecting both demographic and lifestyle changes, which have resulted in genomic...
10.
Arsic N, Slatter T, Gadea G, Villain E, Fournet A, Kazantseva M, et al.
Nat Commun
. 2021 Sep;
12(1):5463.
PMID: 34526502
The p53 isoform, Δ133p53β, is critical in promoting cancer. Here we report that Δ133p53β activity is regulated through an aggregation-dependent mechanism. Δ133p53β aggregates were observed in cancer cells and tumour...