Marina Kazantseva
Overview
Explore the profile of Marina Kazantseva including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
148
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Recent Articles
1.
Wiles A, Mehta S, Millier M, Woolley A, Li K, Parker K, et al.
Arthritis Res Ther
. 2023 Apr;
25(1):62.
PMID: 37060003
Background: The p53 isoform Δ133p53β is known to be associated with cancers driven by inflammation. Many of the features associated with the development of inflammation in rheumatoid arthritis (RA) parallel...
2.
Arsic N, Slatter T, Gadea G, Villain E, Fournet A, Kazantseva M, et al.
Nat Commun
. 2021 Sep;
12(1):5463.
PMID: 34526502
The p53 isoform, Δ133p53β, is critical in promoting cancer. Here we report that Δ133p53β activity is regulated through an aggregation-dependent mechanism. Δ133p53β aggregates were observed in cancer cells and tumour...
3.
Intronic Polymorphisms Are Associated with Increased Transcript, Immune Infiltration and Cancer Risk
Eiholzer R, Mehta S, Kazantseva M, Drummond C, McKinney C, Young K, et al.
Cancers (Basel)
. 2020 Sep;
12(9).
PMID: 32882831
We investigated the influence of selected SNPs in exon 4 and intron 4 on cancer risk, clinicopathological features and expression of isoforms. The intron 4 SNPs were significantly over-represented in...
4.
Knoepp F, Ashley Z, Barth D, Baldin J, Jennings M, Kazantseva M, et al.
Proc Natl Acad Sci U S A
. 2019 Dec;
117(1):717-726.
PMID: 31871197
Mechanosensitive ion channels are crucial for normal cell function and facilitate physiological function, such as blood pressure regulation. So far little is known about the molecular mechanisms of how channels...
5.
The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer
Kazantseva M, Mehta S, Eiholzer R, Gimenez G, Bowie S, Campbell H, et al.
Cell Death Dis
. 2019 Aug;
10(9):631.
PMID: 31431617
Prostate cancer is the second most common cancer in men, for which there are no reliable biomarkers or targeted therapies. Here we demonstrate that elevated levels of Δ133TP53β isoform characterize...
6.
Kazantseva M, Mehta S, Eiholzer R, Hung N, Wiles A, Slatter T, et al.
Mamm Genome
. 2018 Jul;
29(11-12):831-842.
PMID: 29992419
This review paper outlines studies on the Δ122p53 mouse, a model of the human Δ133p53 isoform, together with studies in other model organisms, cell culture, and where available, clinical investigations....
7.
Kazantseva M, Eiholzer R, Mehta S, Taha A, Bowie S, Roth I, et al.
J Pathol
. 2018 Jun;
246(1):77-88.
PMID: 29888503
As tumor protein 53 (p53) isoforms have tumor-promoting, migration, and inflammatory properties, this study investigated whether p53 isoforms contributed to glioblastoma progression. The expression levels of full-length TP53α (TAp53α) and...
8.
Kazantseva M, Hung N, Mehta S, Roth I, Eiholzer R, Rich A, et al.
Sci Rep
. 2017 May;
7(1):1566.
PMID: 28484276
Accumulating evidence suggests tumor protein 53 (p53) promotes correct cellular differentiation. Thus, mutant TP53 may be more frequent in tumors with irregular differentiation. This study investigated whether TP53 mutations were...