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Suna Lahut

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Articles 6
Citations 127
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Recent Articles
1.
Vural A, Simsir G, Tekgul S, Kocoglu C, Akcimen F, Kartal E, et al.
Mov Disord . 2021 Feb; 36(7):1676-1688. PMID: 33624863
Background: The genetic and epidemiological features of hereditary ataxias have been reported in several populations; however, Turkey is still unexplored. Due to high consanguinity, recessive ataxias are more common in...
2.
Lahut S, Gispert S, Omur O, Depboylu C, Seidel K, Dominguez-Bautista J, et al.
Dis Model Mech . 2017 Jan; 10(5):619-631. PMID: 28108469
Parkinson's disease (PD) is a frequent neurodegenerative process in old age. Accumulation and aggregation of the lipid-binding SNARE complex component α-synuclein (SNCA) underlies this vulnerability and defines stages of disease...
3.
Ozoguz A, Uyan O, Birdal G, Iskender C, Kartal E, Lahut S, et al.
Neurobiol Aging . 2015 Feb; 36(4):1764.e9-1764.e18. PMID: 25681989
The frequency of amyotrophic lateral sclerosis (ALS) mutations has been extensively investigated in several populations; however, a systematic analysis in Turkish cases has not been reported so far. In this...
4.
Auburger G, Gispert S, Lahut S, Omur O, Damrath E, Heck M, et al.
World J Diabetes . 2014 Jun; 5(3):316-27. PMID: 24936253
Genetic linkage analyses, genome-wide association studies of single nucleotide polymorphisms, copy number variation surveys, and mutation screenings found the human chromosomal 12q24 locus, with the genes SH2B3 and ATXN2 in...
5.
Lahut S, Vadasz D, Depboylu C, Ries V, Krenzer M, Stiasny-Kolster K, et al.
Neurogenetics . 2014 May; 15(3):189-92. PMID: 24863655
Gain-of-function mutations of alpha-synuclein (SNCA) are known to trigger Parkinson's disease (PD) with striatal dopaminergic deficits and a reduction of spontaneous movements. The longest size variant (allele 2) of the...
6.
Lahut S, Omur O, Uyan O, Agim Z, Ozoguz A, Parman Y, et al.
PLoS One . 2012 Aug; 7(8):e42956. PMID: 22916186
Expansions of the polyglutamine (polyQ) domain (≥ 34) in Ataxin-2 (ATXN2) are the primary cause of spinocerebellar ataxia type 2 (SCA2). Recent studies reported that intermediate-length (27-33) expansions increase the...