Sumedha Roy
Overview
Explore the profile of Sumedha Roy including associated specialties, affiliations and a list of published articles.
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37
Citations
201
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Recent Articles
1.
Radtke K, Bender B, Li Z, Turner D, Roy S, Belousov A, et al.
Clin Cancer Res
. 2024 Nov;
31(2):245-257.
PMID: 39556515
Cytokine release syndrome (CRS) is a common acute toxicity in T-cell therapies, including T-cell-engaging bispecific antibodies (T-BiSp). Effective CRS management and prevention are crucial in T-BiSp development. Required hospitalization for...
2.
Mihai A, Roy S, Krangel M, Zhuang Y
Front Immunol
. 2023 Jul;
14:1188738.
PMID: 37483636
V(D)J recombination of antigen receptor loci is a highly developmentally regulated process. During T lymphocyte development, recombination of the gene occurs in CD4CD8 double positive (DP) thymocytes and requires the...
3.
Roy S, Fitzgerald K, Lalani A, Lai C, Kim A, Kim J, et al.
J Clin Invest
. 2023 Jun;
133(12).
PMID: 37317970
While the rapid advancement of immunotherapies has revolutionized cancer treatment, only a small fraction of patients derive clinical benefit. Eradication of large, established tumors appears to depend on engaging and...
4.
Rajak P, Roy S, Podder S, Dutta M, Sarkar S, Ganguly A, et al.
Toxicol Appl Pharmacol
. 2022 Oct;
456:116267.
PMID: 36240863
Organophosphates (OPs) are ubiquitous environmental contaminants, widely used as pesticides in agricultural fields. In addition, they serve as flame-retardants, plasticizers, antifoaming or antiwear agents in lacquers, hydraulic fluids, and floor...
5.
Ratiu J, Barclay W, Lin E, Wang Q, Wellford S, Mehta N, et al.
Nat Commun
. 2022 Oct;
13(1):5901.
PMID: 36202870
Production of a functional peripheral T cell compartment typically involves massive expansion of the bone marrow progenitors that seed the thymus. There are two main phases of expansion during T...
6.
Roy S, Mandal N, Ray A, Roy P, Bhattacharyya A, Saha P
Asian J Psychiatr
. 2022 May;
76:103133.
PMID: 35551878
Background: Attention Deficit/ Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental psychiatric disorders of childhood. Treatment of ADHD includes medications and Behavioural interventions. Neurofeedback, a type of biofeedback,...
7.
Rajak P, Roy S, Pal A, Paramanik M, Dutta M, Podder S, et al.
Curr Res Toxicol
. 2021 Dec;
2:411-423.
PMID: 34917955
Rotenone is a broad-spectrum pesticide employed in various agricultural practices all over the world. Human beings are exposed to this chemical through oral, nasal, and dermal routes. Inhalation of rotenone...
8.
Rajak P, Roy S, Dutta M, Podder S, Sarkar S, Ganguly A, et al.
Reprod Biol
. 2021 Sep;
21(4):100559.
PMID: 34547545
COVID-19 is the ongoing health emergency affecting individuals of all ages around the globe. Initially, the infection was reported to affect pulmonary structures. However, recent studies have delineated the impacts...
9.
Rajak P, Ganguly A, Sarkar S, Mandi M, Dutta M, Podder S, et al.
Food Chem Toxicol
. 2021 Jan;
149:112007.
PMID: 33493637
Consistent gathering of immunotoxic substances on earth is a serious global issue affecting people under pathogenic stress. Organophosphates are among such hazardous compounds that are ubiquitous in nature. They fuel...
10.
Wang Q, Lin Y, Zhang B, Wu J, Roy S, Ratiu J, et al.
Proc Natl Acad Sci U S A
. 2020 Oct;
117(45):28212-28220.
PMID: 33106431
Somatic mutations are major genetic contributors to cancers and many other age-related diseases. Many disease-causing somatic mutations can initiate clonal growth prior to the appearance of any disease symptoms, yet...