Suman Pokhrel
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Explore the profile of Suman Pokhrel including associated specialties, affiliations and a list of published articles.
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58
Citations
1255
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Recent Articles
1.
Martuza M, Pokhrel S, Stahl J, Schowalter M, Rosenauer A, Madler L
Small
. 2025 Mar;
:e2409993.
PMID: 40059462
The objective of this study is to investigate the influence of various process parameters, such as the fuel-to-oxygen ratio, precursor flow rate, co-flow rate, and different metal-to-sulfur ratios on the...
2.
Elezaby A, Lin A, Vijayan V, Pokhrel S, Kraemer B, Bechara L, et al.
Nat Cardiovasc Res
. 2024 Aug;
3(8):987-1002.
PMID: 39196031
Cardiac troponin I (cTnI) is a key regulator of cardiomyocyte contraction. However, its role in mitochondria is unknown. Here we show that cTnI localized to mitochondria in the heart, inhibited...
3.
Scott-Fordsmand J, Gomes S, Pokhrel S, Madler L, Fasano M, Asinari P, et al.
ACS Appl Mater Interfaces
. 2024 Aug;
16(32):42862-42872.
PMID: 39087586
The wide variation of nanomaterial (NM) characters (size, shape, and properties) and the related impacts on living organisms make it virtually impossible to assess their safety; the need for modeling...
4.
Groeneveld J, Pokhrel S, Madler L
Nanoscale Horiz
. 2024 May;
9(6):956-967.
PMID: 38742382
Nanoparticles exhibit superior physical and chemical properties, making them highly desirable for various applications. Flame spray pyrolysis (FSP) is a versatile technique for synthesizing size and composition-controlled metal oxide/sulfide nanoparticles...
5.
Rios L, Pokhrel S, Li S, Heo G, Haileselassie B, Mochly-Rosen D
Nat Commun
. 2023 Jul;
14(1):4356.
PMID: 37468472
The large cytosolic GTPase, dynamin-related protein 1 (Drp1), mediates both physiological and pathological mitochondrial fission. Cell stress triggers Drp1 binding to mitochondrial Fis1 and subsequently, mitochondrial fragmentation, ROS production, metabolic...
6.
Pokhrel S, Stahl J, Groeneveld J, Schowalter M, Rosenauer A, Birkenstock J, et al.
Adv Mater
. 2023 Apr;
35(28):e2211104.
PMID: 37029337
The development of a novel reactive spray technology based on the well-known gas-phase metal oxide synthesis route provides innumerable opportunities for the production of non-oxide nanoparticles. Among these materials, metal...
7.
Sanders B, Pokhrel S, Labbe A, Mathews I, Cooper C, Davidson R, et al.
Nat Commun
. 2023 Mar;
14(1):1733.
PMID: 36977673
Direct-acting antivirals are needed to combat coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). The papain-like protease (PLpro) domain of Nsp3 from SARS-CoV-2 is essential...
8.
Hesemans E, Saffarzadeh N, Maksoudian C, Izci M, Chu T, Luci C, et al.
J Nanobiotechnology
. 2023 Mar;
21(1):87.
PMID: 36915084
Nanoparticle-mediated cancer immunotherapy holds great promise, but more efforts are needed to obtain nanoformulations that result in a full scale activation of innate and adaptive immune components that specifically target...
9.
Gomes S, Roca C, Pokhrel S, Madler L, Scott-Fordsmand J, Amorim M
NanoImpact
. 2023 Mar;
30:100458.
PMID: 36858316
The hazards of nanomaterials/nanoparticles (NMs/NPs) are mostly assessed using individual NMs, and a more systematic approach, using many NMs, is needed to evaluate its risks in the environment. Libraries of...
10.
Guo H, Yu X, Liu Y, Paik D, Justesen J, Chandy M, et al.
Sci Transl Med
. 2023 Jan;
15(680):eabp9952.
PMID: 36696485
The common aldehyde dehydrogenase 2 () alcohol flushing variant known as affects ∼8% of the world's population. Even in heterozygous carriers, this missense variant leads to a severe loss of...