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Sujun Chen

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Articles 43
Citations 1867
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Recent Articles
1.
Liu W, Yao Y, Wen J, Huang L, Chen S, Ogaji O, et al.
J Chromatogr A . 2024 Dec; 1740:465597. PMID: 39700610
A rapid and sensitive enrichment technique, field enhanced sample injection-dynamic pH junction-sweeping (FESI-DypH-sweeping) was successfully developed for the simultaneous separation and concentration of alkaloids and stereoisomers of Uncariae ramulus cum...
2.
Li S, Peng Y, Chen M, Zhao Y, Xiong Y, Li J, et al.
Commun Biol . 2024 Sep; 7(1):1200. PMID: 39341906
The continuous generation of multi-omics and phenotype data is propelling advancements in precision oncology. UCSCXenaShiny was developed as an interactive tool for exploring thousands of cancer datasets available on UCSC...
3.
Su P, Liu Y, Chen T, Xue Y, Zeng Y, Zhu G, et al.
Nat Genet . 2024 Sep; 56(9):1890-1902. PMID: 39227744
Functional genomic screens in two-dimensional cell culture models are limited in identifying therapeutic targets that influence the tumor microenvironment. By comparing targeted CRISPR-Cas9 screens in a two-dimensional culture with xenografts...
4.
Chen G, Wang W, Wei X, Chen Y, Peng L, Qu R, et al.
J Pathol . 2024 Aug; 264(3):250-269. PMID: 39161125
Testicular tumors represent the most common malignancy among young men. Nevertheless, the pathogenesis and molecular underpinning of testicular tumors remain largely elusive. We aimed to delineate the intricate intra-tumoral heterogeneity...
5.
Wang S, Zeng Y, Zhu L, Zhang M, Zhou L, Yang W, et al.
Cancer Discov . 2024 Jun; 14(11):2279-2299. PMID: 38922581
Comprehensive N6-methyladenosine (m6A) epitranscriptomic profiling of primary tumors remains largely uncharted. Here, we profiled the m6A epitranscriptome of 10 nonneoplastic lung tissues and 51 lung adenocarcinoma (LUAD) tumors, integrating the...
6.
Ci X, Chen S, Zhu R, Zarif M, Jain R, Guo W, et al.
BMC Cancer . 2024 Jun; 24(1):744. PMID: 38890593
Background: Tumor hypoxia is associated with prostate cancer (PCa) treatment resistance and poor prognosis. Pimonidazole (PIMO) is an investigational hypoxia probe used in clinical trials. A better understanding of the...
7.
Chen S, Katsonis N, Leigh D, Patanapongpibul M, Ryabchun A, Zhang L
Angew Chem Int Ed Engl . 2024 Mar; 63(18):e202401291. PMID: 38445723
The transmission of chiral information between the molecular, meso and microscopic scales is a facet of biology that remains challenging to understand mechanistically and to mimic with artificial systems. Here...
8.
Peng X, Jiang L, Chen S, Feng H
Pacing Clin Electrophysiol . 2024 Feb; 47(9):1206-1208. PMID: 38407401
A 67-year-old male presented with symptomatic bradycardia caused by atrial fibrillation and underwent His bundle pacing (HBP) and left bundle branch pacing (LBBP). Electrocardiography (ECG) revealed a complete right bundle...
9.
Lo N, He H, Chen S
Front Oncol . 2023 Sep; 13:1185013. PMID: 37692852
Liquid biopsy is emerging as an intriguing tool in clinical disease detection and monitoring. Compared to a standard tissue biopsy, performing a liquid biopsy incurs minimal invasiveness, captures comprehensive disease...
10.
Wang Z, Petricca J, Liu M, Zhang S, Chen S, Li M, et al.
Proc Natl Acad Sci U S A . 2023 Aug; 120(33):e2220472120. PMID: 37549269
Dysregulation of histone lysine methyltransferases and demethylases is one of the major mechanisms driving the epigenetic reprogramming of transcriptional networks in castration-resistant prostate cancer (CRPC). In addition to their canonical...