Sue L Jaspersen
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Explore the profile of Sue L Jaspersen including associated specialties, affiliations and a list of published articles.
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69
Citations
2167
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Recent Articles
1.
Kunchala P, Varberg J, OToole E, Gardner J, Smith S, McClain M, et al.
Curr Biol
. 2024 Jul;
34(15):3416-3428.e4.
PMID: 39043187
Karyotypes, composed of chromosomes, must be accurately partitioned by the mitotic spindle for optimal cell health. However, it is unknown how underlying characteristics of karyotypes, such as chromosome number and...
2.
Jaspersen S, Stacy A, McGlynn M, Gooch C, Wilson D, Bolton K
Pediatr Blood Cancer
. 2024 Apr;
71(7):e30991.
PMID: 38602302
No abstract available.
3.
Jaspersen S, Bruns D, Candee M, Battaglia A, Carey J, Fishler K
Am J Med Genet A
. 2023 Jan;
191(4):1026-1037.
PMID: 36601988
Changes in medical intervention over the last decade have improved outcomes for individuals with trisomy 18, the second most common human aneuploidy syndrome at birth. As children with trisomy 18...
4.
King G, Wettstein R, Varberg J, Chetlapalli K, Walsh M, Gillet L, et al.
J Cell Biol
. 2022 Dec;
222(2).
PMID: 36515990
Nuclear pore complexes (NPCs) are large proteinaceous assemblies that mediate nuclear compartmentalization. NPCs undergo large-scale structural rearrangements during mitosis in metazoans and some fungi. However, our understanding of NPC remodeling...
5.
6.
Shelton S, Smith S, Jaspersen S
Methods Mol Biol
. 2022 Apr;
2502:205-213.
PMID: 35412240
Defining the proteome of any given subcellular compartment provides insight into the activities and functions within that organelle. Understanding the composition of the nuclear envelope (NE) using traditional methods such...
7.
Varberg J, Unruh J, Bestul A, Khan A, Jaspersen S
Life Sci Alliance
. 2022 Mar;
5(7).
PMID: 35354597
The number, distribution, and composition of nuclear pore complexes (NPCs) in the nuclear envelope varies between cell types and changes during cellular differentiation and in disease. To understand how NPC...
8.
Akey C, Singh D, Ouch C, Echeverria I, Nudelman I, Varberg J, et al.
Cell
. 2022 Jan;
185(2):361-378.e25.
PMID: 34982960
Nuclear pore complexes (NPCs) mediate the nucleocytoplasmic transport of macromolecules. Here we provide a structure of the isolated yeast NPC in which the inner ring is resolved by cryo-EM at...
9.
Shelton S, Smith S, Unruh J, Jaspersen S
G3 (Bethesda)
. 2021 Dec;
11(12).
PMID: 34849801
The inner nuclear membrane (INM) proteome regulates gene expression, chromatin organization, and nuclear transport; however, it is poorly understood how changes in INM protein composition contribute to developmentally regulated processes,...
10.
Gardner J, OToole E, Jaspersen S
MicroPubl Biol
. 2021 Sep;
2021.
PMID: 34549174
and are two paralogs that encode transmembrane proteins of the nuclear envelope (NE) involved in membrane fluidity and nuclear pore complex biogenesis in organisms that undergo a closed mitosis. We...