Sudipa Ghimire-Rijal
Overview
Explore the profile of Sudipa Ghimire-Rijal including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
206
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Belmontes B, Slemmons K, Su C, Liu S, Policheni A, Moriguchi J, et al.
Cancer Discov
. 2024 Sep;
15(1):139-161.
PMID: 39282709
One of the most robust synthetic lethal interactions observed in multiple functional genomic screens has been the dependency on protein arginine methyltransferase 5 (PRMT5) in cancer cells with MTAP deletion....
2.
Mock M, Jacobitz A, Langmead C, Sudom A, Yoo D, Humphreys S, et al.
MAbs
. 2023 Sep;
15(1):2256745.
PMID: 37698932
Biologic drug discovery pipelines are designed to deliver protein therapeutics that have exquisite functional potency and selectivity while also manifesting biophysical characteristics suitable for manufacturing, storage, and convenient administration to...
3.
Wurz R, Rui H, Dellamaggiore K, Ghimire-Rijal S, Choi K, Smither K, et al.
Nat Commun
. 2023 Jul;
14(1):4177.
PMID: 37443112
Targeted protein degradation via "hijacking" of the ubiquitin-proteasome system using proteolysis targeting chimeras (PROTACs) has evolved into a novel therapeutic modality. The design of PROTACs is challenging; multiple steps involved...
4.
Bai Y, Yu X, Chen H, Horne D, White R, Wu X, et al.
Elife
. 2020 Mar;
9.
PMID: 32149605
Transient receptor potential canonical (TRPC) proteins form nonselective cation channels that play physiological roles in a wide variety of cells. Despite growing evidence supporting the therapeutic potential of TRPC6 inhibition...
5.
Lu X, Selvaraj B, Ghimire-Rijal S, Orf G, Meilleur F, Blankenship R, et al.
Acta Crystallogr F Struct Biol Commun
. 2019 Mar;
75(Pt 3):171-175.
PMID: 30839291
The Fenna-Matthews-Olson protein from Prosthecochloris aestuarii (PaFMO) has been crystallized in a new form that is amenable to high-resolution X-ray and neutron analysis. The crystals belonged to space group H3,...
6.
Li L, Ghimire-Rijal S, Lucas S, Stanley C, Wright E, Agarwal P, et al.
Biochemistry
. 2017 Sep;
56(40):5328-5337.
PMID: 28876049
The ligand-induced conformational changes of periplasmic binding proteins (PBP) play a key role in the acquisition of metabolites in ATP binding cassette (ABC) transport systems. This conformational change allows for...
7.
Ghimire-Rijal S, Lu X, Myles D, Cuneo M
J Biol Chem
. 2014 Sep;
289(43):30090-100.
PMID: 25210043
Many bacteria exist in a state of feast or famine where high nutrient availability leads to periods of growth followed by nutrient scarcity and growth stagnation. To adapt to the...
8.
Comparative thermodynamic analysis of zinc binding to the His/Cys motif in virion infectivity factor
Ghimire-Rijal S, Maynard Jr E
Inorg Chem
. 2014 Apr;
53(9):4295-302.
PMID: 24735396
HIV-1 virion infectivity factor (Vif) is an accessory protein that induces the proteasomal degradation of the host restriction factor, apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G). Degradation of APOBEC3G...
9.
Munshi P, Stanley C, Ghimire-Rijal S, Lu X, Myles D, Cuneo M
BMC Struct Biol
. 2013 Oct;
13:18.
PMID: 24090243
Background: Members of the periplasmic binding protein (PBP) superfamily utilize a highly conserved inter-domain ligand binding site that adapts to specifically bind a chemically diverse range of ligands. This paradigm...
10.
Nandal A, Ruiz J, Subramanian P, Ghimire-Rijal S, Sinnamon R, Stemmler T, et al.
Cell Metab
. 2011 Nov;
14(5):647-57.
PMID: 22055506
Mammalian cells express dozens of iron-containing proteins, yet little is known about the mechanism of metal ligand incorporation. Human poly (rC) binding protein 1 (PCBP1) is an iron chaperone that...