Sudhish Sharma
Overview
Explore the profile of Sudhish Sharma including associated specialties, affiliations and a list of published articles.
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26
Citations
397
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Recent Articles
1.
Guru S, Saha P, Chen L, Tulshyan A, Ge Z, Baily J, et al.
Stem Cell Rev Rep
. 2023 Jun;
19(6):2038-2051.
PMID: 37261668
Stem cell therapy provides a hope to no option heart disease patient group. Stem cells work via different mechanisms of which paracrine mechanism is reported to justify most of the...
2.
Bilewska A, Mishra R, Stefanowicz A, Sharma S, Mehta V, Kaushal S
Postepy Kardiol Interwencyjnej
. 2023 Mar;
18(4):319-325.
PMID: 36967848
Hypoplastic left heart syndrome (HLHS) is one of the most complex forms of congenital heart disease, characterized by an underdeveloped left ventricle, outflow tract and aorta. Current surgical and medical...
3.
Bilewska A, Abdullah M, Mishra R, Musialek P, Gunasekaran M, Saha P, et al.
Postepy Kardiol Interwencyjnej
. 2023 Mar;
18(4):431-438.
PMID: 36967844
Introduction: Stem cell-based therapies have shown promise in adults with ischemic cardiomyopathy and children with congenital heart diseases, especially those without available therapeutic options. Human neonatal mesenchymal stem cells (nMSCs)...
4.
Mishra R, Saha P, Datla S, Mellacheruvu P, Gunasekaran M, Guru S, et al.
J Transl Med
. 2023 Mar;
21(1):168.
PMID: 36869398
No abstract available.
5.
Fu X, Mishra R, Chen L, Arfat M, Sharma S, Kingsbury T, et al.
iScience
. 2023 Feb;
26(2):105963.
PMID: 36818289
Cardiac fibrosis is a hallmark in late-stage familial dilated cardiomyopathy (DCM) patients, although the underlying mechanism remains elusive. Cardiac exosomes (Exos) have been reported relating to fibrosis in ischemic cardiomyopathy....
6.
Mishra R, Saha P, Datla S, Mellacheruvu P, Gunasekaran M, Guru S, et al.
J Transl Med
. 2022 Jul;
20(1):323.
PMID: 35864544
Background: Despite promising results in clinical studies, the mechanism for the beneficial effects of allogenic cell-based therapies remains unclear. Macrophages are not only critical mediators of inflammation but also critical...
7.
Gunasekaran M, Mishra R, Saha P, Morales D, Cheng W, Jayaraman A, et al.
iScience
. 2022 Jul;
25(8):104656.
PMID: 35847554
Successful cell therapy requires cells to resist the hostile ischemic myocardium, be retained to continue secreting cardioprotective growth factors/exosomes, and resist immunological host responses. Clinically relevant stem/progenitor cells in a...
8.
Kaushal S, Hare J, Shah A, Pietris N, Bettencourt J, Piller L, et al.
Pediatr Cardiol
. 2022 Apr;
43(7):1481-1493.
PMID: 35394149
Mortality in infants with hypoplastic left heart syndrome (HLHS) is strongly correlated with right ventricle (RV) dysfunction. Cell therapy has demonstrated potential improvements of RV dysfunction in animal models related...
9.
Saha P, Kim M, Tulshyan A, Guo Y, Mishra R, Li D, et al.
J Thorac Cardiovasc Surg
. 2021 Sep;
165(2):e56-e65.
PMID: 34465468
Objective: After cardiac injury, endogenous repair mechanisms are ineffective. However, cell-based therapies provide a promising clinical intervention based on their ability to restore and remodel injured myocardium due to their...
10.
Abdullah M, Kegel S, Gunasekaran M, Saha P, Fu X, Mishra R, et al.
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu
. 2021 Jun;
24:67-76.
PMID: 34116785
Current surgical and medical treatment options for single ventricle physiology conditions remain palliative. On the long term, despite treatment, the systemic ventricle has a significant risk of developing failure. There...