Sunjay Kaushal
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Explore the profile of Sunjay Kaushal including associated specialties, affiliations and a list of published articles.
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101
Citations
1124
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Recent Articles
1.
de Miguel-Perez D, Arroyo-Hernandez M, La Salvia S, Gunasekaran M, Pickering E, Avila S, et al.
J Extracell Vesicles
. 2024 Nov;
13(11):e70001.
PMID: 39558820
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19) and has been related to more than 7 million deaths globally since 2019. The association of high...
2.
Baumgardt S, Fang J, Fu X, Liu Y, Xia Z, Zhao M, et al.
Cardiovasc Res
. 2024 Jul;
120(12):1456-1471.
PMID: 39001869
Aims: The histone deacetylase 6 (HDAC6) inhibitor, tubastatin A (TubA), reduces myocardial ischaemia/reperfusion injury (MIRI) in type 1 diabetic rats. It remains unclear whether HDAC6 regulates MIRI in type 2...
3.
Saha P, Guru S, Ge Z, Simms L, Chen L, Bolli R, et al.
Stem Cell Rev Rep
. 2024 Jun;
20(7):1843-1853.
PMID: 38941039
Intravenous infusion has been used as the method of cell delivery in many preclinical studies as well as in some early clinical trials. Among its advantages are broad distribution, ability...
4.
Wang G, Lu W, Shen W, Karbowski M, Kaushal S, Yang P
JACC Basic Transl Sci
. 2024 Apr;
9(3):303-318.
PMID: 38559623
Most congenital heart defect (CHD) cases are attributed to nongenetic factors; however, the mechanisms underlying nongenetic factor-induced CHDs are elusive. Maternal diabetes is one of the nongenetic factors, and this...
5.
Hoffman J, Park H, Bheri S, Platt M, Hare J, Kaushal S, et al.
iScience
. 2023 Oct;
26(10):107980.
PMID: 37868626
Cardiac-derived c-kit+ progenitor cells (CPCs) are under investigation in the CHILD phase I clinical trial (NCT03406884) for the treatment of hypoplastic left heart syndrome (HLHS). The therapeutic efficacy of CPCs...
6.
Guru S, Saha P, Chen L, Tulshyan A, Ge Z, Baily J, et al.
Stem Cell Rev Rep
. 2023 Jun;
19(6):2038-2051.
PMID: 37261668
Stem cell therapy provides a hope to no option heart disease patient group. Stem cells work via different mechanisms of which paracrine mechanism is reported to justify most of the...
7.
Sinha A, Guru S, Varadarajan S, Alvarez A, Kaushal S, Fu X
Stem Cell Res
. 2023 Apr;
69:103092.
PMID: 37086582
We generated a new iPSC line (LCHi003-A) from the pediatric dilated cardiomyopathy patient carrying the de novo mutation on DNM1L gene. The new iPSC line expressed high pluripotent markers and...
8.
Li X, Fan H, Song X, Song B, Liu W, Dong R, et al.
Epigenetics
. 2023 Apr;
18(1):2195307.
PMID: 37005704
Hypertrophic cardiomyopathy (HCM) is the most common inherited heart disease. However, a detailed DNA methylation (DNAme) landscape has not yet been elucidated. Our study combined DNAme and transcriptome profiles for...
9.
Bilewska A, Mishra R, Stefanowicz A, Sharma S, Mehta V, Kaushal S
Postepy Kardiol Interwencyjnej
. 2023 Mar;
18(4):319-325.
PMID: 36967848
Hypoplastic left heart syndrome (HLHS) is one of the most complex forms of congenital heart disease, characterized by an underdeveloped left ventricle, outflow tract and aorta. Current surgical and medical...
10.
Bilewska A, Abdullah M, Mishra R, Musialek P, Gunasekaran M, Saha P, et al.
Postepy Kardiol Interwencyjnej
. 2023 Mar;
18(4):431-438.
PMID: 36967844
Introduction: Stem cell-based therapies have shown promise in adults with ischemic cardiomyopathy and children with congenital heart diseases, especially those without available therapeutic options. Human neonatal mesenchymal stem cells (nMSCs)...