Sudarshan Anand
Overview
Explore the profile of Sudarshan Anand including associated specialties, affiliations and a list of published articles.
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37
Citations
1509
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Recent Articles
1.
Rahman S, Affleck 4th A, Ruhl R, Patel R, Gao L, Brinkerhoff B, et al.
Dis Colon Rectum
. 2024 Mar;
67(7):940-950.
PMID: 38479005
Background: The tumor immune microenvironment is distinct between early-onset and late-onset colorectal cancer, which facilitates tumor progression. We previously identified several genes, including complement factor D, as having increased expression...
2.
Brooks D, Anand S, Cohen M
Curr Opin Chem Biol
. 2023 Oct;
77:102402.
PMID: 37801755
PARPs encompass a small yet pervasive group of 17 enzymes that catalyze a post-translational modification known as ADP-ribosylation. PARP1, the founding member, has received considerable focus; however, in recent years,...
3.
Baris A, Fraile-Bethencourt E, Eubanks J, Khou S, Anand S
Cell Death Dis
. 2023 Apr;
14(4):294.
PMID: 37100811
Activation of nucleic acid sensors in endothelial cells (ECs) has been shown to drive inflammation across pathologies including cancer, atherosclerosis and obesity. We previously showed that enhancing cytosolic DNA sensing...
4.
Watson K, Siemens K, Anand S, Gardner I, Sharpton T, Dewey E, et al.
Gut Pathog
. 2022 Dec;
14(1):49.
PMID: 36564812
Background: Microbial dysbiosis has been closely linked with colorectal cancer development. However, data is limited regarding the relationship of the mucosal microbiome, adenomatous polyps and dietary habits. Understanding these associations...
5.
Fraile-Bethencourt E, Foss M, Nelson D, V Malhotra S, Anand S
Front Mol Biosci
. 2022 Mar;
9:837610.
PMID: 35237663
Enhancing the immune microenvironment in cancer by targeting the nucleic acid sensors is becoming a potent therapeutic strategy. Among the nucleic acid sensors, activation of the RNA sensor Retinoic Acid-inducible...
6.
Watson K, Gardner I, Anand S, Siemens K, Sharpton T, Kasschau K, et al.
Ann Surg
. 2022 Feb;
277(4):e817-e824.
PMID: 35129506
Objective: We aimed to examine associations between the oral, fecal, and mucosal microbiome communities and adenoma formation. Summary Background Data: Data are limited regarding the relationships between microbiota and preneoplastic...
7.
Baris A, Fraile-Bethencourt E, Anand S
Cancers (Basel)
. 2021 Sep;
13(17).
PMID: 34503262
Endothelial cells form a powerful interface between tissues and immune cells. In fact, one of the underappreciated roles of endothelial cells is to orchestrate immune attention to specific sites. Tumor...
8.
Chatterjee N, Fraile-Bethencourt E, Baris A, Espinosa-Diez C, Anand S
Front Cell Dev Biol
. 2021 Jul;
9:671461.
PMID: 34322482
Defects in stress responses are important contributors in many chronic conditions including cancer, cardiovascular disease, diabetes, and obesity-driven pathologies like non-alcoholic steatohepatitis (NASH). Specifically, endoplasmic reticulum (ER) stress is linked...
9.
Sun Y, Chen W, Torphy R, Yao S, Zhu G, Lin R, et al.
Sci Transl Med
. 2021 Jul;
13(604).
PMID: 34321321
The immature and dysfunctional vascular network within solid tumors poses a substantial obstacle to immunotherapy because it creates a hypoxic tumor microenvironment that actively limits immune cell infiltration. The molecular...
10.
Gardner I, Siddharthan R, Watson K, Dewey E, Ruhl R, Khou S, et al.
Immunohorizons
. 2021 Jun;
5(6):489-499.
PMID: 34162701
Despite a decrease in the prevalence of colorectal cancer (CRC) over the last 40 y, the prevalence of CRC in people under 50 y old is increasing around the globe....