Subramaniam Eswaramoorthy
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Explore the profile of Subramaniam Eswaramoorthy including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Eswaramoorthy S, Sun J, Li H, Singh B, Swaminathan S
Sci Rep
. 2015 Dec;
5:17795.
PMID: 26639353
Clostridium botulinum neurotoxin (BoNT) is released as a progenitor complex, in association with a non-toxic-non-hemagglutinin protein (NTNH) and other associated proteins. We have determined the crystal structure of M type...
2.
Ghasempur S, Eswaramoorthy S, Hillerich B, Seidel R, Swaminathan S, Almo S, et al.
Biochemistry
. 2014 May;
53(20):3357-66.
PMID: 24831290
The l-lyxonate dehydratase (LyxD) in vitro enzymatic activity and in vivo metabolic function were assigned to members of an isofunctional family within the mandelate racemase (MR) subgroup of the enolase...
3.
Goble A, Toro R, Li X, Ornelas A, Fan H, Eswaramoorthy S, et al.
Biochemistry
. 2013 Aug;
52(37):6525-36.
PMID: 23972005
Proteins of unknown function belonging to cog1816 and cog0402 were characterized. Sav2595 from Steptomyces avermitilis MA-4680, Acel0264 from Acidothermus cellulolyticus 11B, Nis0429 from Nitratiruptor sp. SB155-2 and Dr0824 from Deinococcus...
4.
Eswaramoorthy S, Poulain S, Hienerwadel R, Bremond N, Sylvester M, Zhang Y, et al.
PLoS One
. 2012 May;
7(4):e36017.
PMID: 22558308
The Escherichia coli ChrR enzyme is an obligatory two-electron quinone reductase that has many applications, such as in chromate bioremediation. Its crystal structure, solved at 2.2 Å resolution, shows that...
5.
Kumari S, Eswaramoorthy S, Mathias R, Varadaraj K
Biochim Biophys Acta
. 2011 Apr;
1812(9):1089-97.
PMID: 21511033
Aquaporin (AQP) 1 and AQP0 water channels are expressed in lens epithelial and fiber cells, respectively, facilitating fluid circulation for nourishing the avascular lens to maintain transparency. Even though AQP0...
6.
Lakshminarasimhan D, Eswaramoorthy S, Burley S, Swaminathan S
Acta Crystallogr Sect F Struct Biol Cryst Commun
. 2010 Jan;
66(Pt 1):8-11.
PMID: 20057058
The crystal structure of the hypothetical protein YqgQ from Bacillus subtilis has been determined to 2.1 A resolution. The crystals belonged to space group P2(1), with unit-cell parameters a =...
7.
Kumaran D, Eswaramoorthy S, Furey W, Navaza J, Sax M, Swaminathan S
J Mol Biol
. 2009 Jan;
386(1):233-45.
PMID: 19118561
Clostridium botulinum produces seven antigenically distinct neurotoxins [C. botulinum neurotoxins (BoNTs) A-G] sharing a significant sequence homology. Based on sequence and functional similarity, it was believed that their three-dimensional structures...
8.
Tyagi R, Eswaramoorthy S, Burley S, Raushel F, Swaminathan S
Biochemistry
. 2008 Apr;
47(20):5608-15.
PMID: 18442260
Imidazolonepropionase (HutI) (imidazolone-5-propanote hydrolase, EC 3.5.2.7) is a member of the amidohydrolase superfamily and catalyzes the conversion of imidazolone-5-propanoate to N-formimino-L-glutamate in the histidine degradation pathway. We have determined the...
9.
Madegowda M, Eswaramoorthy S, Burley S, Swaminathan S
Proteins
. 2008 Jan;
71(2):534-40.
PMID: 18175317
Bacillus cereus Hemolysin BL enterotoxin, a ternary complex of three proteins, is the causative agent of food poisoning and requires all three components for virulence. The X-ray structure of the...
10.
Almo S, Bonanno J, Sauder J, Emtage S, DiLorenzo T, Malashkevich V, et al.
J Struct Funct Genomics
. 2007 Dec;
8(2-3):121-40.
PMID: 18058037
The New York SGX Research Center for Structural Genomics (NYSGXRC) of the NIGMS Protein Structure Initiative (PSI) has applied its high-throughput X-ray crystallographic structure determination platform to systematic studies of...