Subhashini Sadasivam
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Explore the profile of Subhashini Sadasivam including associated specialties, affiliations and a list of published articles.
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10
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914
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Recent Articles
1.
Ghanekar Y, Sadasivam S
Bioinform Biol Insights
. 2022 Apr;
16:11779322221088725.
PMID: 35462874
Background: Rheumatoid arthritis (RA) is an autoimmune disease characterised by systemic inflammation of joints. The observed complexity of RA pathogenesis and studies that have been carried out so far indicate...
2.
Sadasivam S, Subramanian R
Front Biosci (Landmark Ed)
. 2020 Mar;
25(6):1011-1021.
PMID: 32114422
Cancer stem cells (CSCs) or tumor-initiating cells (TICs) represent a minority population of cells in a tumor that can self-renew and re-create the heterogeneity of the entire tumor. Cell lines,...
3.
Ghanekar Y, Sadasivam S
PeerJ
. 2019 Feb;
7:e6402.
PMID: 30775178
Background: Sequencing studies across multiple cancers continue to reveal mutations and genes involved in the pathobiology of these cancers. Exome sequencing of oral cancers, a subset of Head and Neck...
4.
Mishra A, Sriram H, Chandarana P, Tanavde V, Kumar R, Gopinath A, et al.
Tumour Biol
. 2018 Jun;
40(5):1010428318780859.
PMID: 29888653
The goal of this study was to isolate cancer stem-like cells marked by high expression of CD44, a putative cancer stem cell marker, from primary oral squamous cell carcinomas and...
5.
Sadasivam S, DeCaprio J
Nat Rev Cancer
. 2013 Jul;
13(8):585-95.
PMID: 23842645
The dimerization partner, RB-like, E2F and multi-vulval class B (DREAM) complex provides a previously unsuspected unifying role in the cell cycle by directly linking p130, p107, E2F, BMYB and forkhead...
6.
Rodig S, Cheng J, Wardzala J, DoRosario A, Scanlon J, Laga A, et al.
J Clin Invest
. 2012 Nov;
122(12):4645-53.
PMID: 23114601
A human polyomavirus was recently discovered in Merkel cell carcinoma (MCC) specimens. The Merkel cell polyomavirus (MCPyV) genome undergoes clonal integration into the host cell chromosomes of MCC tumors and...
7.
Sadasivam S, Duan S, DeCaprio J
Genes Dev
. 2012 Mar;
26(5):474-89.
PMID: 22391450
Cell cycle progression is dependent on two major waves of gene expression. Early cell cycle gene expression occurs during G1/S to generate factors required for DNA replication, while late cell...
8.
Litovchick L, Sadasivam S, Florens L, Zhu X, Swanson S, Velmurugan S, et al.
Mol Cell
. 2007 May;
26(4):539-51.
PMID: 17531812
The mammalian Retinoblastoma (RB) family including pRB, p107, and p130 represses E2F target genes through mechanisms that are not fully understood. In D. melanogaster, RB-dependent repression is mediated in part...
9.
Thalappilly S, Sadasivam S, Radha V, Swarup G
FEBS J
. 2006 Jul;
273(12):2766-78.
PMID: 16817903
PTP-S2/TC45 is a nuclear protein tyrosine phosphatase that activates p53 and induces caspase 1-dependent apoptosis. We analyzed the role of ICE protease-activating factor (Ipaf), an activator of caspase 1 in...
10.
Sadasivam S, Gupta S, Radha V, Batta K, Kundu T, Swarup G
Oncogene
. 2004 Dec;
24(4):627-36.
PMID: 15580302
The tumor suppressor protein p53 regulates transcription of many genes that mediate cell cycle arrest, apoptosis, DNA repair and other cellular responses. Here we show that Ipaf, a human CED-4...