Stuart C Feinstein
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Explore the profile of Stuart C Feinstein including associated specialties, affiliations and a list of published articles.
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59
Citations
1425
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Recent Articles
1.
Tchounwou C, Jobanputra A, Lasher D, Fletcher B, Jacinto J, Bhaduri A, et al.
Langmuir
. 2024 Sep;
40(40):21041-21051.
PMID: 39340452
Tau, an intrinsically disordered neuronal protein and polyampholyte with an overall positive charge, is a microtubule (MT) associated protein that binds to anionic domains of MTs and suppresses their dynamic...
2.
Tchounwou C, Jobanputra A, Lasher D, Fletcher B, Jacinto J, Bhaduri A, et al.
bioRxiv
. 2024 Jul;
PMID: 39071287
Tau, an intrinsically disordered neuronal protein and polyampholyte with an overall positive charge, is a microtubule (MT) associated protein, which binds to anionic domains of MTs and suppresses their dynamic...
3.
Kohl P, Song C, Fletcher B, Best R, Tchounwou C, Garcia Arceo X, et al.
Nat Commun
. 2024 Mar;
15(1):2362.
PMID: 38491006
The axon-initial-segment (AIS) of mature neurons contains microtubule (MT) fascicles (linear bundles) implicated as retrograde diffusion barriers in the retention of MT-associated protein (MAP) tau inside axons. Tau dysfunction and...
4.
Cho H, Lee J, Nho H, Lee K, Gim B, Lee J, et al.
Eur Phys J E Soft Matter
. 2023 Aug;
46(9):73.
PMID: 37653246
Aggregated and hyperphosphorylated Tau is one of the pathological hallmarks of Alzheimer's disease. Tau is a polyampholytic and intrinsically disordered protein (IDP). In this paper, we present for the first...
5.
Aralis Z, Comer S, Ansorg H, Palmer C, Smith J, Feinstein S, et al.
Diagnostics (Basel)
. 2022 Nov;
12(11).
PMID: 36428863
The emergence of the SARS-CoV-2 Omicron variant in 2021 is associated with a global surge of cases in late 2021 and early 2022. Identifying the introduction of novel SARS-CoV-2 variants...
6.
Chung P, Song C, Deek J, Miller H, Li Y, Choi M, et al.
ACS Macro Lett
. 2022 May;
7(2):228-232.
PMID: 35610898
The proliferation of successful, cell-free reconstitutions of cytoskeletal networks have prompted measurements of forces between network elements via induced osmotic pressure by the addition of depletants. Indeed, it was through...
7.
Best R, LaPointe N, Azarenko O, Miller H, Genualdi C, Chih S, et al.
Toxicol Appl Pharmacol
. 2021 Apr;
421:115534.
PMID: 33852878
Monomethyl auristatin E (MMAE) is a potent anti-cancer microtubule-targeting agent (MTA) used as a payload in three approved MMAE-containing antibody drug conjugates (ADCs) and multiple ADCs in clinical development to...
8.
Lee J, Song C, Lee J, Miller H, Cho H, Gim B, et al.
Small
. 2020 Aug;
16(37):e2001240.
PMID: 32794304
By virtue of their native structures, tubulin dimers are protein building blocks that are naturally preprogrammed to assemble into microtubules (MTs), which are cytoskeletal polymers. Here, polycation-directed (i.e., electrostatically tunable)...
9.
Safinya C, Chung P, Song C, Li Y, Miller H, Choi M, et al.
Langmuir
. 2019 Sep;
35(48):15970-15978.
PMID: 31539262
In this minireview, which is part of a special issue in honor of Jacob N. Israelachvili's remarkable research career on intermolecular forces and interfacial science, we present studies of structures,...
10.
Best R, LaPointe N, Liang J, Ruan K, Shade M, Wilson L, et al.
J Biol Chem
. 2019 Jul;
294(33):12265-12280.
PMID: 31266806
The microtubule (MT)-associated protein tau regulates the critical growing and shortening behaviors of MTs, and its normal activity is essential for neuronal development and maintenance. Accordingly, aberrant tau action is...