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Stewart F Graham

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Articles 64
Citations 997
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Recent Articles
1.
Yilmaz A, Akyol S, Ashrafi N, Saiyed N, Turkoglu O, Graham S
Metabolites . 2025 Jan; 15(1). PMID: 39852353
Background: Huntington's disease (HD) is a multifaceted neurological disorder characterized by the progressive deterioration of motor, cognitive, and psychiatric functions. Despite a limited understanding of its pathogenesis, research has implicated...
2.
Bahado-Singh R, Ashrafi N, Ibrahim A, Aydas B, Yilmaz A, Friedman P, et al.
Sci Rep . 2025 Jan; 15(1):2060. PMID: 39814838
Prenatal sonographic diagnosis of congenital heart disease (CHD) can lead to improved morbidity and mortality. However, the diagnostic accuracy of ultrasound, the sole prenatal screening tool, remains limited. Failed prenatal...
3.
Clarke E, Gomez-Martin M, Stanford J, Yilmaz A, Ustun I, Wood L, et al.
Nutrients . 2025 Jan; 16(24. PMID: 39770979
Background/objectives: Thus far, no studies have examined the relationship between fruit and vegetable (F and V) intake, urinary metabolite quantities, and weight change. Therefore, the aim of the current study...
4.
Vishweswaraiah S, Yilmaz A, Gordevicius J, Milciute M, Krinickis K, Kerseviciute I, et al.
Mov Disord . 2024 Dec; PMID: 39736077
Background: Lewy body diseases, including dementia with Lewy bodies (DLB), are characterized by α-synuclein accumulation, leading to dementia. Previous studies suggest distinct epigenetic and metabolomic profiles in DLB. Objective: This...
5.
Zararsiz G, Lintelmann J, Cecil A, Kirwan J, Poschet G, Gegner H, et al.
bioRxiv . 2024 Nov; PMID: 39605511
Metabolomics and lipidomics are pivotal in understanding phenotypic variations beyond genomics. However, quantification and comparability of mass spectrometry (MS)-derived data are challenging. Standardised assays can enhance data comparability, enabling applications...
6.
Sink W, Fling R, Yilmaz A, Nault R, Goniwiecha D, Harkema J, et al.
bioRxiv . 2024 Nov; PMID: 39484576
Epidemiological evidence suggests an association between dioxin and dioxin-like compound (DLC) exposure and human liver disease. The prototypical DLC, 2,3,7,8-tetrachlorodibenzo--dioxin (TCDD), has been shown to induce the progression of reversible...
7.
Turkoglu O, Citil A, Katar C, Mert I, Quinn R, Bahado-Singh R, et al.
Int J Mol Sci . 2024 Oct; 25(19). PMID: 39408663
Ectopic pregnancy (EP) is the leading cause of maternal morbidity and mortality in the first trimester. Using an untargeted metabolomic approach, we sought to identify putative plasma biomarkers using tandem...
8.
Yadav A, MacNeill J, Krylov A, Ashrafi N, Mimi R, Saxena R, et al.
Hepatol Commun . 2024 Aug; 8(9). PMID: 39185904
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is strongly associated with obesity. Sex and age affect MASLD prevalence and pathophysiology. The use of animal models fed Western-style diets is vital...
9.
Idler J, Turkoglu O, Yilmaz A, Ashrafi N, Szymanska M, Ustun I, et al.
Metabolomics . 2024 May; 20(3):56. PMID: 38762675
Introduction: Preeclampsia (PreE) remains a major source of maternal and newborn complications. Prenatal prediction of these complications could significantly improve pregnancy management. Objectives: Using metabolomic analysis we investigated the prenatal...
10.
Guzior D, Okros M, Shivel M, Armwald B, Bridges C, Fu Y, et al.
Nature . 2024 Feb; 626(8000):852-858. PMID: 38326608
Bile acids (BAs) are steroid detergents in bile that contribute to the absorption of fats and fat-soluble vitamins while shaping the gut microbiome because of their antimicrobial properties. Here we...