Bernadette McGuinness
Overview
Explore the profile of Bernadette McGuinness including associated specialties, affiliations and a list of published articles.
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108
Citations
6597
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Recent Articles
1.
Glover S, Illyuk J, Hill C, McGuinness B, McKnight A, Hunter R
Environ Epigenet
. 2025 Jan;
11(1):dvae027.
PMID: 39882510
The increasing prevalence of neurodegenerative diseases poses a significant public health challenge, prompting a growing focus on addressing modifiable risk factors of disease (e.g. physical inactivity, mental illness, and air...
2.
Vishweswaraiah S, Yilmaz A, Gordevicius J, Milciute M, Krinickis K, Kerseviciute I, et al.
Mov Disord
. 2024 Dec;
PMID: 39736077
Background: Lewy body diseases, including dementia with Lewy bodies (DLB), are characterized by α-synuclein accumulation, leading to dementia. Previous studies suggest distinct epigenetic and metabolomic profiles in DLB. Objective: This...
3.
Hunter R, Cleland C, Trott M, ONeill S, Kucukali H, Mullineaux S, et al.
BMJ Open
. 2024 Dec;
14(12):e085318.
PMID: 39658284
Introduction: Maintaining cognitive health in later life is a global priority. Encouraging individuals to make health behaviour changes, such as regular physical activity, and providing supportive urban environments can help...
4.
Shawaqfeh B, Hughes C, McGuinness B, Barry H
Int J Clin Pharm
. 2024 Nov;
PMID: 39585549
Background: Anticholinergic medications and associated anticholinergic burden can impair cognitive function and increase mortality rates in patients with dementia. Aim: To explore community pharmacists' knowledge of anticholinergic burden and perceptions...
5.
Potter C, Hill C, Smyth L, Neville C, Scott A, Kee F, et al.
BMJ Open
. 2024 Sep;
14(9):e085652.
PMID: 39277204
Purpose: Epigenetic modifications including DNA methylation (DNAm) are proposed mechanisms by which social or environmental exposures may influence health and behaviours as we age. The Northern Ireland Cohort for the...
6.
Shawaqfeh B, Hughes C, McGuinness B, Barry H
Health Expect
. 2024 Aug;
27(1):e13972.
PMID: 39102656
Introduction: There is concern about the use of anticholinergic medications in people living with dementia (PLWD). Such medicines may increase cognitive decline and may be associated with higher mortality in...
7.
Marr C, McDowell B, Holmes C, Edwards C, Cardwell C, McHenry M, et al.
J Alzheimers Dis
. 2024 Apr;
99(1):161-175.
PMID: 38669538
Background: Evidence suggests that TNF inhibitors (TNFi) used to treat rheumatoid arthritis (RA) may protect against Alzheimer's disease progression by reducing inflammation. Objective: To investigate whether RA patients with mild...
8.
OHara L, Neville C, Marr C, McAlinden M, Kee F, Weir D, et al.
BMJ Open
. 2024 Jan;
14(1):e075672.
PMID: 38296305
Introduction: The Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) study is the largest study of ageing in Northern Ireland (NI). The Harmonised Cognitive Assessment Protocol (HCAP) is...
9.
Pan X, Donaghy P, Roberts G, Chouliaras L, OBrien J, Thomas A, et al.
Front Aging Neurosci
. 2024 Jan;
15:1326780.
PMID: 38239488
Background: In multifactorial diseases, alterations in the concentration of metabolites can identify novel pathological mechanisms at the intersection between genetic and environmental influences. This study aimed to profile the plasma...
10.
Ward N, Reid-McCann R, Brennan L, Cardwell C, de Groot C, Maggi S, et al.
BMJ Open
. 2023 Oct;
13(10):e070689.
PMID: 37880167
Introduction: Undernutrition leading to unplanned weight loss is common in older age and has been linked to increased dementia risk in later life. Weight loss can precede dementia by a...