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Steven Vermeulen

Explore the profile of Steven Vermeulen including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 808
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Recent Articles
1.
Vermeulen S, Rosado Balmayor E
Biomater Biosyst . 2024 Jul; 14:100096. PMID: 38974419
The nucleus serves as the central hub for cellular activity, driving cell identity and behavior. Despite its crucial role, understanding how biomaterials influence the nucleus remains an underexplored area of...
2.
Vermeulen S, Knoops K, Duimel H, Parvizifard M, van Beurden D, Lopez-Iglesias C, et al.
Mater Today Bio . 2023 Nov; 23:100844. PMID: 38033367
A challenge in regenerative medicine is creating the three-dimensional organic and inorganic microenvironment of bone, which would allow the study of musculoskeletal disorders and the generation of building blocks for...
3.
Vermeulen S, Van Puyvelde B, Bengtsson Del Barrio L, Almey R, van der Veer B, Deforce D, et al.
Adv Sci (Weinh) . 2022 Nov; :e2203880. PMID: 36414384
Biomaterials can control cell and nuclear morphology. Since the shape of the nucleus influences chromatin architecture, gene expression and cell identity, surface topography can control cell phenotype. This study provides...
4.
Eren A, Vermeulen S, Schmitz T, Foolen J, de Boer J
Acta Biomater . 2022 May; 163:275-286. PMID: 35584748
Cells and their surrounding extracellular matrix (ECM) are engaged in dynamic reciprocity to maintain tissue homeostasis: cells deposit ECM, which in turn presents the signals that define cell identity. This...
5.
Vermeulen S, Tahmasebi Birgani Z, Habibovic P
Biomaterials . 2022 Mar; 283:121431. PMID: 35231787
Embryogenic developmental processes involve a tightly controlled regulation between mechanical forces and biochemical cues such as growth factors, matrix proteins, and cytokines. This interplay remains essential in the mature body,...
6.
Tuvshindorj U, Trouillet V, Vasilevich A, Koch B, Vermeulen S, Carlier A, et al.
Small . 2022 Jan; 18(10):e2105704. PMID: 34985808
In vivo cells reside in a complex extracellular matrix (ECM) that presents spatially distributed biochemical and -physical cues at the nano- to micrometer scales. Chemical micropatterning is successfully used to...
7.
Vermeulen S, Honig F, Vasilevich A, Roumans N, Romero M, Eren A, et al.
Adv Mater . 2021 Jun; 33(31):e2102084. PMID: 34165820
Surface topography is a tool to endow biomaterials with bioactive properties. However, the large number of possible designs makes it challenging to find the optimal surface structure to induce a...
8.
Burroughs L, Amer M, Vassey M, Koch B, Figueredo G, Mukonoweshuro B, et al.
Biomaterials . 2021 Mar; 271:120740. PMID: 33714019
Human mesenchymal stem cells (hMSCs) are widely represented in regenerative medicine clinical strategies due to their compatibility with autologous implantation. Effective bone regeneration involves crosstalk between macrophages and hMSCs, with...
9.
Vasilevich A, Vermeulen S, Kamphuis M, Roumans N, Eroume S, Hebels D, et al.
Sci Rep . 2020 Nov; 10(1):18988. PMID: 33149200
Learning rules by which cell shape impacts cell function would enable control of cell physiology and fate in medical applications, particularly, on the interface of cells and material of the...
10.
Vermeulen S, Roumans N, Honig F, Carlier A, Hebels D, Eren A, et al.
Biomaterials . 2020 Aug; 259:120331. PMID: 32836056
We previously found that surface topographies induce the expression of the Scxa gene, encoding Scleraxis in tenocytes. Because Scxa is a TGF-β responsive gene, we investigated the link between mechanotransduction...