Steven T Russell
Overview
Explore the profile of Steven T Russell including associated specialties, affiliations and a list of published articles.
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19
Citations
430
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Recent Articles
1.
Brimson J, Akula K, Abbas H, Ferry D, Kulkarni S, Russell S, et al.
Sci Rep
. 2020 Jun;
10(1):9251.
PMID: 32514120
Sigma-1 and sigma-2 receptors are emerging therapeutic targets. We have identified that simple ammonium salts bind to these receptors and are effective in vivo. Radioligand binding assays were used to...
2.
Claudius A, Kankipati C, Kilari R, Hassan S, Guest K, Russell S, et al.
Oncol Rep
. 2014 Aug;
32(4):1670-80.
PMID: 25109257
Substantial evidence indicates that aspirin and related non-steroidal anti-inflammatory drugs (NSAIDs) have potential as chemopreventative/therapeutic agents. However, these agents cannot be universally recommended for prevention purposes due to their potential...
3.
Russell S, Tisdale M
Endocrinology
. 2012 Aug;
153(10):4696-704.
PMID: 22903615
Zinc-α2-glycoprotein (ZAG) is an adipokine with the potential as a therapeutic agent in the treatment of obesity and type 2 diabetes. In this study we show that human ZAG, which...
4.
Russell S, Tisdale M
Endocrinology
. 2010 Aug;
151(10):4696-704.
PMID: 20702573
The mechanism by which the adipokine zinc-α2-glycoprotein (ZAG) increases the mass of gastrocnemius, but not soleus muscle of diabetic mice, has been evaluated both in vivo and in vitro. There...
5.
Russell S, Tisdale M
Endocrinology
. 2009 Dec;
151(3):948-57.
PMID: 20032055
Zinc-alpha(2)-glycoprotein (ZAG) is an adipokine associated with fat loss in cancer cachexia. The purpose of this study was to evaluate the ability of recombinant human ZAG to attenuate type 2...
6.
Russell S, Siren P, Siren M, Tisdale M
Exp Cell Res
. 2009 Sep;
316(2):286-95.
PMID: 19716818
D-myo-inositol 1,2,6-triphosphate (alpha trinositol, AT) has been shown to attenuate muscle atrophy in a murine cachexia model through an increase in protein synthesis and a decrease in degradation. The mechanism...
7.
Russell S, Tisdale M
Mol Cell Biochem
. 2009 May;
330(1-2):171-9.
PMID: 19404720
The mechanism of the effect of beta-hydroxy-beta-methylbutyrate (HMB) on protein degradation induced by lipopolysaccharide (LPS) has been evaluated in murine myotubes. HMB (50 muM) completely attenuated total protein degradation induced...
8.
Russell S, Rajani S, Dhadda R, Tisdale M
Exp Cell Res
. 2008 Nov;
315(1):16-25.
PMID: 18973755
Treatment of murine myotubes with high glucose concentrations (10 and 25 mM) stimulated protein degradation through the ubiquitin-proteasome pathway, and also caused activation (autophosphorylation) of PKR (double-stranded-RNA-dependent protein kinase) and...
9.
Eley H, Russell S, Tisdale M
Am J Physiol Endocrinol Metab
. 2008 Oct;
295(6):E1409-16.
PMID: 18854427
beta-Hydroxy-beta-methylbutyrate (HMB; 50 microM) has been shown to attenuate the depression in protein synthesis in murine myotubes in response to lipopolysaccharide (LPS), tumor necrosis factor-alpha (TNF-alpha) with or without interferon-gamma...
10.
Eley H, Russell S, Tisdale M
Am J Physiol Endocrinol Metab
. 2008 Oct;
295(6):E1417-26.
PMID: 18840762
Both tumor necrosis factor-alpha (TNF-alpha)/interferon-gamma (IFN-gamma) and angiotensin II (ANG II) induced an increase in total protein degradation in murine myotubes, which was completely attenuated by treatment with beta-hydroxy-beta-methylbutyrate (HMB;...