Shrinivas K Kulkarni
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Explore the profile of Shrinivas K Kulkarni including associated specialties, affiliations and a list of published articles.
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94
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1445
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Recent Articles
1.
Brimson J, Akula K, Abbas H, Ferry D, Kulkarni S, Russell S, et al.
Sci Rep
. 2020 Jun;
10(1):9251.
PMID: 32514120
Sigma-1 and sigma-2 receptors are emerging therapeutic targets. We have identified that simple ammonium salts bind to these receptors and are effective in vivo. Radioligand binding assays were used to...
2.
Pissurlenkar R, Dhir A, Kessar S, Kulkarni S, Coutinho E
Cent Nerv Syst Agents Med Chem
. 2011 Sep;
11(3):228-37.
PMID: 21919867
Dysfunction of serotoninergic neurotransmission is known to be involved in the pathophysiology of major depression. The molecules that enhance the level of serotonin either via blocking serotonin reuptake or through...
3.
Pabreja K, Dua K, Sharma S, Padi S, Kulkarni S
Eur J Pharmacol
. 2011 May;
661(1-3):15-21.
PMID: 21536024
Painful neuropathy, a common complication of diabetes mellitus is characterized by allodynia and hyperalgesia. Recent studies emphasized on the role of non-neuronal cells, particularly microglia in the development of neuronal...
4.
Bishnoi M, Chopra K, Rongzhu L, Kulkarni S
Neurotox Res
. 2010 Nov;
20(3):215-25.
PMID: 21076901
Long-term treatment with haloperidol is associated with a number of extrapyramidal side effects, particularly the irregular movements of chorionic type. This limitation presents a marked therapeutic challenge. The present study...
5.
Guangwei X, Rongzhu L, Wenrong X, Suhua W, Xiaowu Z, Shizhong W, et al.
Toxicology
. 2009 Nov;
267(1-3):140-6.
PMID: 19913070
Acrylonitrile (AN) is widely used in the manufacturing of fibers, plastics and pharmaceuticals. Free radical-mediated lipid peroxidation is implicated in the toxicity of AN. The present study was designed to...
6.
Kulkarni S, Dhir A
Expert Rev Neurother
. 2009 Jul;
9(7):1021-34.
PMID: 19589051
Major depression and anxiety are two of the major psychiatric disorders that have some overlapping pathophysiologies, the most significant being the dysfunction in the monoaminergic, GABAergic and glutamatergic systems. A...
7.
Kulkarni S, Dhir A
Expert Opin Investig Drugs
. 2009 May;
18(6):767-88.
PMID: 19426122
Background: The World Health Organization (WHO) report has predicted that major depression will become a key cause of illness-induced disability by the year 2020, second only to ischemic heart diseases....
8.
Kulkarni S, Bishnoi M, Chopra K
Indian J Exp Biol
. 2009 Apr;
47(2):91-7.
PMID: 19374163
Therapeutic success of atypical antipsychotics has focused the attention on the role of receptor systems other than dopaminergic system in the pathophysiology of neuroleptics-associated acute (Parkinson's like syndrome) and chronic...
9.
Bhutani M, Bishnoi M, Kulkarni S
Pharmacol Biochem Behav
. 2008 Nov;
92(1):39-43.
PMID: 19000708
Curcumin, a yellow pigment extracted from rhizomes of the plant Curcuma longa (turmeric), has been widely used as food additive and also as a herbal medicine throughout Asia. The present...
10.
Padi S, Kulkarni S
Eur J Pharmacol
. 2008 Oct;
601(1-3):79-87.
PMID: 18952075
Glia, particularly astrocytes and microglia, are known to play an important role in central sensitization and are strongly implicated in the exaggerated pain states. In the present study, we determined...