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Steven D Shapiro

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Articles 172
Citations 6407
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Recent Articles
11.
Giordano L, Gregory A, Perez Verdaguer M, Ware S, Harvey H, DeVallance E, et al.
Cells . 2022 Feb; 11(3). PMID: 35159179
Cigarette smoke (CS) is the most common risk factor for chronic obstructive pulmonary disease (COPD). The present study aimed to elucidate whether mtDNA is released upon CS exposure and is...
12.
Dicpinigaitis A, Palumbo K, Gandhi C, Cooper J, Hanft S, Kamal H, et al.
Cerebrovasc Dis . 2022 Feb; 51(5):565-569. PMID: 35158366
Background: Previous literature has identified a survival advantage in acute ischemic stroke (AIS) patients with elevated body mass indices (BMIs), a phenomenon termed the "obesity paradox." Objective: The aim of...
13.
Feldstein E, Zeller S, Mureb M, Kamal H, Shapiro S, Kaur G, et al.
Clin Neurol Neurosurg . 2022 Feb; 214:107172. PMID: 35158165
Congenital variants of the aortic arch are important to recognize not only for their association with congenital heart disease, vascular rings, and chromosomal abnormalities but also for the purposes of...
14.
Shapiro S, Alkayyali M, Reynolds A, Reilly K, Selim M, Dangayach N, et al.
World Neurosurg . 2022 Feb; 161:e289-e294. PMID: 35134583
Background: Recent publications on minimally invasive surgery (MIS) for hematoma evacuation have suggested survival benefits in select patients. Since 2015, our center has been performing an MIS technique using continuous...
15.
Dicpinigaitis A, Gandhi C, Shah S, Galea V, Cooper J, Feldstein E, et al.
J Neurol Sci . 2022 Feb; 434:120168. PMID: 35101765
Introduction: The safety and efficacy of intravenous thrombolysis (IVT) before endovascular thrombectomy (EVT) for large vessel occlusion stroke remains a highly contested and unanswered clinical question. We aim to characterize...
16.
Alder J, Sutton R, Iasella C, Nouraie M, Koshy R, Hannan S, et al.
J Heart Lung Transplant . 2021 Dec; 41(5):654-663. PMID: 34933798
Background: Idiopathic pulmonary fibrosis (IPF) is the most common indication for lung transplantation in North America and variants in telomere-maintenance genes are the most common identifiable cause of IPF. We...
17.
Chu X, Sun Z, Baek D, Li W, Mellors J, Shapiro S, et al.
Int J Mol Sci . 2021 Oct; 22(20). PMID: 34681796
Neutrophil elastase (NE) is a serine protease released during neutrophil maturation. High levels of NE are related to lung tissue damage and poor prognosis in cancer; thus, NE is a...
18.
Chen D, Gregory A, Li X, Wei J, Burton C, Gibson G, et al.
JCI Insight . 2021 Jun; 6(12). PMID: 34156033
Necroptosis has emerged as a potential mechanism in the pathogenesis of chronic obstructive pulmonary disease (COPD). Here, we found that markers of necroptosis, including high mobility group box 1 release...
19.
Sun F, Li L, Xiao Y, Gregory A, Shapiro S, Xiao G, et al.
J Immunol . 2021 Jun; 207(1):110-114. PMID: 34135059
Macrophages play a central role in lung physiology and pathology. In this study, we show in mice that alveolar macrophages (AMs), unlike other macrophage types (interstitial, peritoneal, and splenic macrophages),...
20.
Carleton N, Zou J, Fang Y, Koscumb S, Shah O, Chen F, et al.
JAMA Netw Open . 2021 Apr; 4(4):e216322. PMID: 33856473
Importance: Overtreatment of early-stage breast cancer with favorable tumor biology in older patients may be harmful without affecting recurrence and survival. Guidelines that recommend deimplementation of sentinel lymph node biopsy...