Steven Balk
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Explore the profile of Steven Balk including associated specialties, affiliations and a list of published articles.
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11
Citations
506
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Recent Articles
1.
Ummarino S, Poluben L, Ebralidze A, Autiero I, Ebralidze A, Zhang Y, et al.
Res Sq
. 2025 Feb;
PMID: 39975922
Coordinated initiation of DNA replication is essential to ensure efficient and timely DNA synthesis. Yet, molecular mechanism describing how replication initiation is coordinated in eukaryotic cells is not completely understood....
2.
Awasthi S, Berglund A, Abraham-Miranda J, Rounbehler R, Kensler K, Serna A, et al.
Clin Cancer Res
. 2020 Oct;
27(1):320-329.
PMID: 33037017
Purpose: The role of immune-oncologic mechanisms of racial disparities in prostate cancer remains understudied. Limited research exists to evaluate the molecular underpinnings of immune differences in African American men (AAM)...
3.
Alsinnawi M, Zhang A, Bianchi-Frias D, Burns J, Cho E, Zhang X, et al.
Prostate Cancer Prostatic Dis
. 2019 Mar;
22(4):560-568.
PMID: 30890759
Background: SLCO-encoded transporters have been associated with progression to castration-resistant prostate cancer (CRPC) after initiation of androgen deprivation therapy (ADT). Although expressed at lower levels than in CRPC tissues, SLCO-encoded...
4.
Kolodny G, Li X, Balk S
Bioessays
. 2018 Aug;
40(10):e1800057.
PMID: 30101540
Major problems in cancer chemotherapy are toxicity, resistance, and cancer heterogeneity. A new theranostic paradigm has been proposed by the authors. Many million small molecules (SM) are bound to the...
5.
Challenges in Interpreting Germline Mutations in BARD1 and ATM in Breast and Ovarian Cancer Patients
DeLeonardis K, Sedgwick K, Voznesensky O, Matloff E, Hofstatter E, Balk S, et al.
Breast J
. 2017 Feb;
23(4):461-464.
PMID: 28139868
Next-generation sequencing promotes identification of mutations in non-BRCA1/2 genes in hereditary cancer families. The contribution of mutations in moderate penetrance genes to hereditary cancer risk is not well established. Here,...
6.
Mostaghel E, Nelson P, Lange P, Lin D, Taplin M, Balk S, et al.
J Clin Oncol
. 2013 Dec;
32(3):229-37.
PMID: 24323034
Purpose: Ligand-mediated activation of the androgen receptor (AR) is critical for prostate cancer (PCa) survival and proliferation. The failure to completely ablate tissue androgens may limit suppression of PCa growth....
7.
Tamae D, Byrns M, Marck B, Mostaghel E, Nelson P, Lange P, et al.
J Steroid Biochem Mol Biol
. 2013 Jul;
138:281-9.
PMID: 23851165
Prostate cancer is the most frequently diagnosed form of cancer in males in the United States. The disease is androgen driven and the use of orchiectomy or chemical castration, known...
8.
Sun T, Yang M, Chen S, Balk S, Pomerantz M, Hsieh C, et al.
Prostate
. 2011 Dec;
72(10):1093-103.
PMID: 22127852
Background: We have previously identified seven miRs-miR-221, -222, -23b, -27b, -15a, -16-1, and -203, that are differentially expressed in the hormone sensitive LNCaP cell line and the hormone resistant LNCaP-abl...
9.
Yang M, Xie W, Mostaghel E, Nakabayashi M, Werner L, Sun T, et al.
J Clin Oncol
. 2011 May;
29(18):2565-73.
PMID: 21606417
Purpose: Androgen deprivation therapy (ADT), an important treatment for advanced prostate cancer, is highly variable in its effectiveness. We hypothesized that genetic variants of androgen transporter genes, SLCO2B1 and SLCO1B3,...
10.
Sun T, Wang Q, Balk S, Brown M, Lee G, Kantoff P
Cancer Res
. 2009 Apr;
69(8):3356-63.
PMID: 19351832
Androgen-dependent prostate cancer typically progresses to castration-resistant prostate cancer (CRPC) after the androgen deprivation therapy. MicroRNAs (miR) are noncoding small RNAs (19-25nt) that play an important role in the regulation...