Steven B Marston
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Explore the profile of Steven B Marston including associated specialties, affiliations and a list of published articles.
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61
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1690
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Recent Articles
1.
Yang Z, Sheehan A, Messer A, Tsui S, Sparrow A, Redwood C, et al.
Front Physiol
. 2024 Dec;
15:1489439.
PMID: 39735723
Introduction: Adrenergic activation of protein kinase A (PKA) in cardiac muscle targets the sarcolemma, sarcoplasmic reticulum, and contractile apparatus to increase contractile force and heart rate. In the thin filaments...
2.
Yang Z, Marston S, Gould I
J Phys Chem B
. 2023 Oct;
127(41):8736-8748.
PMID: 37791815
Adrenaline acts on β1 receptors in the heart muscle to enhance contractility, increase the heart rate, and increase the rate of relaxation (lusitropy) via activation of the cyclic AMP-dependent protein...
3.
Pavadai E, Rynkiewicz M, Yang Z, Gould I, Marston S, Lehman W
Arch Biochem Biophys
. 2022 May;
725:109282.
PMID: 35577070
Tropomyosin, controlled by troponin-linked Ca-binding, regulates muscle contraction by a macromolecular scale steric-mechanism that governs myosin-crossbridge-actin interactions. At low-Ca, C-terminal domains of troponin-I (TnI) trap tropomyosin in a position on...
4.
Vikhorev P, Vikhoreva N, Yeung W, Li A, Lal S, Dos Remedios C, et al.
Cardiovasc Res
. 2020 Nov;
118(1):241-253.
PMID: 33135063
Aims: Dilated cardiomyopathy (DCM) is associated with mutations in many genes encoding sarcomere proteins. Truncating mutations in the titin gene TTN are the most frequent. Proteomic and functional characterizations are...
5.
Tucholski T, Cai W, Gregorich Z, Bayne E, Mitchell S, Mcilwain S, et al.
Proc Natl Acad Sci U S A
. 2020 Sep;
117(40):24691-24700.
PMID: 32968017
Hypertrophic cardiomyopathy (HCM) is the most common heritable heart disease. Although the genetic cause of HCM has been linked to mutations in genes encoding sarcomeric proteins, the ability to predict...
6.
Wright P, Tsui S, Francis A, MacLeod K, Marston S
Front Physiol
. 2020 Aug;
11:612.
PMID: 32733259
The measurement of the contractile behavior of single cardiomyocytes has made a significant contribution to our understanding of the physiology and pathophysiology of the myocardium. However, the isolation of cardiomyocytes...
7.
Ehler E, Marston S
J Muscle Res Cell Motil
. 2019 Jul;
40(2):67.
PMID: 31267353
No abstract available.
8.
Piroddi N, Witjas-Paalberends E, Ferrara C, Ferrantini C, Vitale G, Scellini B, et al.
J Gen Physiol
. 2018 Dec;
151(1):18-29.
PMID: 30578328
Hypertrophic cardiomyopathy (HCM) is a genetic form of left ventricular hypertrophy, primarily caused by mutations in sarcomere proteins. The cardiac remodeling that occurs as the disease develops can mask the...
9.
Vikhorev P, Smoktunowicz N, Munster A, Copeland O, Kostin S, Montgiraud C, et al.
Sci Rep
. 2018 Sep;
8(1):14485.
PMID: 30250041
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
10.
Sheehan A, Messer A, Papadaki M, Choudhry A, Kren V, Biedermann D, et al.
Front Physiol
. 2018 Apr;
9:243.
PMID: 29636697
The inherited cardiomyopathies, hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) are relatively common, potentially life-threatening and currently untreatable. Mutations are often in the contractile proteins of cardiac muscle and cause...