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Stephen Watt

Explore the profile of Stephen Watt including associated specialties, affiliations and a list of published articles. Areas
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Articles 62
Citations 8858
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Recent Articles
11.
Cheung W, Shao X, Morin A, Siroux V, Kwan T, Ge B, et al.
Genome Biol . 2019 May; 20(1):89. PMID: 31064398
Following publication of the original article [1], the authors reported an error in Additional file 1.
12.
Alexander Jr J, Edwards R, Manca L, Grugni R, Bonfanti G, Emir B, et al.
Adv Ther . 2018 Feb; 35(3):382-394. PMID: 29476444
Introduction: Achieving a therapeutic response to pregabalin in patients with painful diabetic peripheral neuropathy (pDPN) requires adequate upward dose titration. Our goal was to identify relationships between titration and response...
13.
Alexander J, Edwards R, Savoldelli A, Manca L, Grugni R, Emir B, et al.
BMC Med Res Methodol . 2017 Jul; 17(1):113. PMID: 28728577
Background: More patient-specific medical care is expected as more is learned about variations in patient responses to medical treatments. Analytical tools enable insights by linking treatment responses from different types...
14.
Cheung W, Shao X, Morin A, Siroux V, Kwan T, Ge B, et al.
Genome Biol . 2017 Mar; 18(1):50. PMID: 28283040
Background: The functional impact of genetic variation has been extensively surveyed, revealing that genetic changes correlated to phenotypes lie mostly in non-coding genomic regions. Studies have linked allele-specific genetic changes...
15.
Ecker S, Chen L, Pancaldi V, Bagger F, Fernandez J, Carrillo De Santa Pau E, et al.
Genome Biol . 2017 Jan; 18(1):18. PMID: 28126036
Background: A healthy immune system requires immune cells that adapt rapidly to environmental challenges. This phenotypic plasticity can be mediated by transcriptional and epigenetic variability. Results: We apply a novel...
16.
Astle W, Elding H, Jiang T, Allen D, Ruklisa D, Mann A, et al.
Cell . 2016 Nov; 167(5):1415-1429.e19. PMID: 27863252
Many common variants have been associated with hematological traits, but identification of causal genes and pathways has proven challenging. We performed a genome-wide association analysis in the UK Biobank and...
17.
Chen L, Ge B, Casale F, Vasquez L, Kwan T, Garrido-Martin D, et al.
Cell . 2016 Nov; 167(5):1398-1414.e24. PMID: 27863251
Characterizing the multifaceted contribution of genetic and epigenetic factors to disease phenotypes is a major challenge in human genetics and medicine. We carried out high-resolution genetic, epigenetic, and transcriptomic profiling...
18.
Freynhagen R, Backonja M, Schug S, Lyndon G, Parsons B, Watt S, et al.
CNS Drugs . 2016 Nov; 30(12):1191-1200. PMID: 27848217
Treatments for physical dependence and associated withdrawal symptoms following the abrupt discontinuation of prescription drugs (such as opioids and benzodiazepines), nicotine, alcohol, and cannabinoids are available, but there is still...
19.
Stanos S, Brodsky M, Argoff C, Clauw D, DArcy Y, Donevan S, et al.
Postgrad Med . 2016 May; 128(5):502-15. PMID: 27166559
Chronic pain substantially impacts patient function and quality of life and is a burden to society at large in terms of increased health care utilization and loss of productivity. As...
20.
Taguchi T, Igarashi A, Watt S, Parsons B, Sadosky A, Nozawa K, et al.
J Pain Res . 2015 Sep; 8:487-97. PMID: 26346468
Objective: To evaluate the impact of pregabalin on sleep, pain, function, and health status in patients with chronic low back pain with accompanying neuropathic pain (CLBP-NeP) under routine clinical practice....