Stephen P Hancock
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Explore the profile of Stephen P Hancock including associated specialties, affiliations and a list of published articles.
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8
Citations
132
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Recent Articles
1.
Soto A, Weldon J, Hancock S
J Microbiol Biol Educ
. 2025 Jan;
e0016524.
PMID: 39807857
In recent years, there has been an increase in the number of course-based undergraduate research experience (CURE) courses. These courses provide research opportunities for many more students than are typically...
2.
Wottrich S, Mendonca S, Safarpour C, Nguyen C, Marinelli L, Hancock S, et al.
Microbiome Res Rep
. 2024 Oct;
3(3):27.
PMID: 39421248
, formerly , is a bacterial species characterized by tenacious acne-contributing pathogenic strains. Therefore, bacteriophage therapy has become an attractive treatment route to circumvent issues such as evolved bacterial antibiotic...
3.
Mycobacteriophage Alexphander Gene Encodes an Essential dsDNA-Binding Protein during Lytic Infection
Chong Qui E, Habtehyimer F, Germroth A, Grant J, Kosanovic L, Singh I, et al.
Int J Mol Sci
. 2024 Jul;
25(13).
PMID: 39000573
Mycobacteriophages are viruses that specifically infect bacterial species within the genera and . Over 2400 mycobacteriophages have been isolated on the host and sequenced. This wealth of genomic data indicates...
4.
Hancock S, Cascio D, Johnson R
Nucleic Acids Res
. 2019 Oct;
47(16):8874-8887.
PMID: 31616952
Localized arrays of proteins cooperatively assemble onto chromosomes to control DNA activity in many contexts. Binding cooperativity is often mediated by specific protein-protein interactions, but cooperativity through DNA structure is...
5.
Chen W, Mandali S, Hancock S, Kumar P, Collazo M, Cascio D, et al.
Elife
. 2018 Oct;
7.
PMID: 30289389
IS-family transposons are unusual because they do not have terminal inverted repeats or generate target site duplications. They encode two protein-coding genes, but only is required for transposition. Our X-ray...
6.
Hancock S, Stella S, Cascio D, Johnson R
PLoS One
. 2016 Mar;
11(3):e0150189.
PMID: 26959646
The abundant Fis nucleoid protein selectively binds poorly related DNA sequences with high affinities to regulate diverse DNA reactions. Fis binds DNA primarily through DNA backbone contacts and selects target...
7.
Shapiro C, Moberg-Parker J, Toma S, Ayon C, Zimmerman H, Roth-Johnson E, et al.
J Microbiol Biol Educ
. 2016 Jan;
16(2):186-97.
PMID: 26751568
This four-year study describes the assessment of a bifurcated laboratory curriculum designed to provide upper-division undergraduate majors in two life science departments meaningful exposure to authentic research. The timing is...
8.
Hancock S, Ghane T, Cascio D, Rohs R, Di Felice R, Johnson R
Nucleic Acids Res
. 2013 May;
41(13):6750-60.
PMID: 23661683
The width of the DNA minor groove varies with sequence and can be a major determinant of DNA shape recognition by proteins. For example, the minor groove within the center...
9.
Hancock S, Hiller D, Perona J, Jen-Jacobson L
J Mol Biol
. 2010 Dec;
406(2):285-312.
PMID: 21167173
DNA bending can be promoted by reducing the net negative electrostatic potential around phosphates on one face of the DNA, such that electrostatic repulsion among phosphates on the opposite face...