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Stephen M Ostrowski

Explore the profile of Stephen M Ostrowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 349
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Recent Articles
1.
Zhang Y, Ostrowski S, Fisher D
Hematol Oncol Clin North Am . 2024 Jun; 38(5):939-952. PMID: 38880666
Cutaneous melanoma is an aggressive form of skin cancer derived from skin melanocytes and is associated with significant morbidity and mortality. A significant fraction of melanomas are associated with precursor...
2.
Bod L, Kye Y, Shi J, Torlai Triglia E, Schnell A, Fessler J, et al.
Nature . 2023 Jun; 619(7969):348-356. PMID: 37344597
The role of B cells in anti-tumour immunity is still debated and, accordingly, immunotherapies have focused on targeting T and natural killer cells to inhibit tumour growth. Here, using high-throughput...
3.
Shreberk-Hassidim R, Ostrowski S, Fisher D
Int J Mol Sci . 2023 Feb; 24(4). PMID: 36834954
One effort to combat the rising incidence of malignant melanoma is focused on early detection by the clinical and dermoscopic screening of melanocytic nevi. However, the interaction between nevi, which...
4.
Moustafa D, Neale H, Ostrowski S, Gellis S, Hawryluk E
Pediatr Dermatol . 2021 Jul; 38 Suppl 2:149-151. PMID: 34272756
Pyogenic granulomas are benign vascular proliferations of the skin and mucous membranes that tend to bleed easily. They typically require procedural treatments that can be difficult for patients with intellectual...
5.
Ostrowski S, Fisher D
Hematol Oncol Clin North Am . 2021 Mar; 35(1):29-56. PMID: 33759772
Melanoma skin cancer is derived from skin melanocytes and has a high risk of metastatic spread. The era of molecular genetics and next-generation sequencing has uncovered the role of oncogenic...
6.
Ostrowski S, Fisher D
J Invest Dermatol . 2021 Jan; 141(2):250-252. PMID: 33504438
Resistance to targeted therapy and immunotherapy remains a major obstacle in improving care for patients with advanced melanoma. MicroRNAs play important roles in regulating gene networks involved in disease progression...
7.
Rachmin I, Ostrowski S, Weng Q, Fisher D
Adv Drug Deliv Rev . 2020 Feb; 153:65-71. PMID: 32092380
Skin pigmentation is a result of melanin produced by melanocytes in the epidermis. Melanocyte activity, along with the type and distribution of melanins, is the main driver for diversity of...
8.
Ostrowski S, Johnson K, Siefert M, Shank S, Sironi L, Wolozin B, et al.
Neuroscience . 2016 May; 329:264-74. PMID: 27180285
Evidence suggests that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, or statins, may reduce the risk of Alzheimer's disease (AD). Statin action in patients with AD, as in those with heart disease,...
9.
Shuda M, Guastafierro A, Geng X, Shuda Y, Ostrowski S, Lukianov S, et al.
PLoS One . 2015 Nov; 10(11):e0142329. PMID: 26544690
Merkel cell polyomavirus (MCV) causes the majority of human Merkel cell carcinomas (MCC) and encodes a small T (sT) antigen that transforms immortalized rodent fibroblasts in vitro. To develop a...
10.
Ostrowski S, Wright M, Bolock A, Geng X, Maricich S
Development . 2015 Jul; 142(14):2533-44. PMID: 26138479
Merkel cells are mechanosensitive skin cells whose production requires the basic helix-loop-helix transcription factor Atoh1. We induced ectopic Atoh1 expression in the skin of transgenic mice to determine whether Atoh1...