Stephen M Cifuni
Overview
Explore the profile of Stephen M Cifuni including associated specialties, affiliations and a list of published articles.
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17
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1408
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Recent Articles
1.
Zitomersky N, Demers M, Martinod K, Gallant M, Cifuni S, Biswas A, et al.
TH Open
. 2018 Jan;
1(1):e11-e23.
PMID: 29376146
Background: Inflammatory bowel disease (IBD) affects 1.6 million people in the United States. IBD is associated with an increased risk of thrombosis, which rises with disease activity. The pathogenesis of...
2.
Hayashi H, Cherpokova D, Martinod K, Witsch T, Wong S, Gallant M, et al.
PLoS One
. 2017 Dec;
12(12):e0188341.
PMID: 29236713
Inflammation is a common denominator in chronic diseases of aging. Yet, how inflammation fuels these diseases remains unknown. Neutrophils are the primary leukocytes involved in the early phase of innate...
3.
Martinod K, Witsch T, Erpenbeck L, Savchenko A, Hayashi H, Cherpokova D, et al.
J Exp Med
. 2016 Dec;
214(2):439-458.
PMID: 28031479
Aging promotes inflammation, a process contributing to fibrosis and decline in organ function. The release of neutrophil extracellular traps (NETs [NETosis]), orchestrated by peptidylarginine deiminase 4 (PAD4), damages organs in...
4.
Erpenbeck L, Demers M, Zsengeller Z, Gallant M, Cifuni S, Stillman I, et al.
J Am Soc Nephrol
. 2015 Jun;
27(1):120-31.
PMID: 26038528
Thrombotic microangiopathy (TMA) is a life-threatening condition that affects some, but not all, recipients of vascular endothelial growth factor (VEGF) inhibitors given as part of chemotherapy. TMA is also a...
5.
Etulain J, Martinod K, Wong S, Cifuni S, Schattner M, Wagner D
Blood
. 2015 May;
126(2):242-6.
PMID: 25979951
Neutrophil extracellular traps (NETs) can be released in the vasculature. In addition to trapping microbes, they promote inflammatory and thrombotic diseases. Considering that P-selectin induces prothrombotic and proinflammatory signaling, we...
6.
Suidan G, Brill A, De Meyer S, Voorhees J, Cifuni S, Cabral J, et al.
Arterioscler Thromb Vasc Biol
. 2013 Jul;
33(9):2112-20.
PMID: 23825365
Objective: Aberrant blood-brain barrier (BBB) permeability is a hallmark pathology of many central nervous system diseases. von Willebrand factor (VWF) is stored in endothelial Weibel-Palade bodies from where it is...
7.
Duerschmied D, Suidan G, Demers M, Herr N, Carbo C, Brill A, et al.
Blood
. 2012 Dec;
121(6):1008-15.
PMID: 23243271
The majority of peripheral serotonin is stored in platelets, which secrete it on activation. Serotonin releases Weibel-Palade bodies (WPBs) and we asked whether absence of platelet serotonin affects neutrophil recruitment...
8.
Thomas G, Carbo C, Curtis B, Martinod K, Mazo I, Schatzberg D, et al.
Blood
. 2012 May;
119(26):6335-43.
PMID: 22596262
Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related death. The biologic processes contributing to TRALI are poorly understood. All blood products can cause TRALI, and no specific...
9.
Jansen A, Josefsson E, Rumjantseva V, Liu Q, Falet H, Bergmeier W, et al.
Blood
. 2011 Nov;
119(5):1263-73.
PMID: 22101895
When refrigerated platelets are rewarmed, they secrete active sialidases, including the lysosomal sialidase Neu1, and express surface Neu3 that remove sialic acid from platelet von Willebrand factor receptor (VWFR), specifically...
10.
Carbo C, Duerschmied D, Goerge T, Hattori H, Sakai J, Cifuni S, et al.
J Leukoc Biol
. 2010 Apr;
88(2):313-9.
PMID: 20413728
Chemotaxis and integrin activation are essential processes for neutrophil transmigration in response to injury. CalDAG-GEFI plays a key role in the activation of beta1, beta2, and beta3 integrins in platelets...