Stephen Hewitt
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Explore the profile of Stephen Hewitt including associated specialties, affiliations and a list of published articles.
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Articles
72
Citations
3310
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Recent Articles
1.
Vocke C, Ricketts C, Pack S, Raffeld M, Hewitt S, Lebensohn A, et al.
J Med Genet
. 2024 Sep;
61(11):1026-1030.
PMID: 39317422
von Hippel-Lindau (VHL) is an autosomal-dominant hereditary tumour susceptibility disease associated with pathogenic germline variants in the tumour suppressor gene. VHL patients are at increased risk of developing multiple benign...
2.
Latt K, Yoshida T, Shrivastav S, Abedini A, Reece J, Sun Z, et al.
Am J Pathol
. 2024 Jul;
194(10):1844-1856.
PMID: 39032602
Although hyponatremia and salt wasting are common in patients with HIV/AIDS, the understanding of their contributing factors is limited. HIV viral protein R (Vpr) contributes to HIV-associated nephropathy. To investigate...
3.
Desai P, Takahashi N, Kumar R, Nichols S, Malin J, Hunt A, et al.
Cell Rep Med
. 2024 Jun;
5(6):101610.
PMID: 38897168
Small-cell lung cancer (SCLC) is the most fatal form of lung cancer. Intratumoral heterogeneity, marked by neuroendocrine (NE) and non-neuroendocrine (non-NE) cell states, defines SCLC, but the cell-extrinsic drivers of...
4.
Jahangir C, Page D, Broeckx G, Gonzalez C, Burke C, Murphy C, et al.
J Pathol
. 2024 Jan;
262(3):271-288.
PMID: 38230434
Recent advances in the field of immuno-oncology have brought transformative changes in the management of cancer patients. The immune profile of tumours has been found to have key value in...
5.
Thagaard J, Broeckx G, Page D, Jahangir C, Verbandt S, Kos Z, et al.
J Pathol
. 2023 Aug;
260(5):498-513.
PMID: 37608772
The clinical significance of the tumor-immune interaction in breast cancer is now established, and tumor-infiltrating lymphocytes (TILs) have emerged as predictive and prognostic biomarkers for patients with triple-negative (estrogen receptor,...
6.
Page D, Broeckx G, Jahangir C, Verbandt S, Gupta R, Thagaard J, et al.
J Pathol
. 2023 Aug;
260(5):514-532.
PMID: 37608771
Modern histologic imaging platforms coupled with machine learning methods have provided new opportunities to map the spatial distribution of immune cells in the tumor microenvironment. However, there exists no standardized...
7.
Latt K, Yoshida T, Shrivastav S, Abedini A, Reece J, Sun Z, et al.
bioRxiv
. 2023 Mar;
PMID: 36945458
Hyponatremia and salt wasting is a common occurance in patients with HIV/AIDS, however, the understanding of its contributing factors is limited. HIV viral protein R (Vpr) contributes to HIV-associated nephropathy....
8.
Shrivastav S, Lee H, Okamoto K, Lu H, Yoshida T, Latt K, et al.
PLoS One
. 2022 Sep;
17(9):e0273313.
PMID: 36129874
HIV-associated nephropathy (HIVAN) impairs functions of both glomeruli and tubules. Attention has been previously focused on the HIVAN glomerulopathy. Tubular injury has drawn increased attention because sodium wasting is common...
9.
Abascal M, Elia A, Alvarez M, Pataccini G, Sequeira G, Riggio M, et al.
Int J Cancer
. 2021 Dec;
150(9):1481-1496.
PMID: 34935137
Progesterone receptors (PRs) ligands are being tested in luminal breast cancer. There are mainly two PR isoforms, PRA and PRB, and their ratio (PRA/PRB) may be predictive of antiprogestin response....
10.
Hodgin J, Mariani L, Zee J, Liu Q, Smith A, Eddy S, et al.
Am J Kidney Dis
. 2021 Dec;
79(6):807-819.e1.
PMID: 34864148
Rationale & Objective: The current classification system for focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) does not fully capture the complex structural changes in kidney biopsies nor the...