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Stephen Hanley

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Recent Articles
1.
Shum-Tim L, Bichara-Allard S, Hopkins B, AlShahwan N, Hanley S, Manzano-Nunez R, et al.
J Trauma Acute Care Surg . 2023 Jul; 96(3):499-509. PMID: 37478348
Background: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is gaining popularity worldwide for managing hypotensive trauma patients. Vascular access complications related to REBOA placement have been reported, with some...
2.
Hanley S
Mcgill J Med . 2011 Jan; 12(2):51. PMID: 21264047
While the prevalence of maternal While the prevalence of diabetes mellitus reaches epidemic proportions, most available treatments still focus on the symptoms of the disease, rather than the underlying pathology....
3.
Assouline-Thomas B, Pilotte A, Petropavlovskaia M, Makhlin J, Ding J, McLeod D, et al.
Protein Expr Purif . 2009 Jul; 69(1):1-8. PMID: 19635567
Islet Neogenesis Associated Protein (INGAP) is implicated in pancreatic islet neogenesis. INGAP peptide, a pentadecapeptide comprising amino acids 104-118, reverses diabetes in rodents and improves glucose homeostasis in patients with...
4.
Hanley S, Rosenberg L
Methods Mol Biol . 2008 Dec; 482:371-85. PMID: 19089368
Current therapies do not prevent the complications of diabetes. Furthermore, these therapies do not address the underlying pathology; the lack of functional beta-cell mass that occurs in both types 1...
5.
Lipsett M, Hanley S, Castellarin M, Austin E, Suarez-Pinzon W, Rabinovitch A, et al.
Cell Biochem Biophys . 2007 Aug; 48(2-3):127-37. PMID: 17709882
Islet Neogenesis-Associated Protein (INGAP) is a member of the Reg family of proteins implicated in various settings of endogenous pancreatic regeneration. The expression of INGAP and other RegIII proteins has...
6.
Hanley S, Rosenberg L
Mol Endocrinol . 2007 Apr; 21(6):1467-77. PMID: 17405902
Tissue plasticity is well documented in the context of pancreatic regeneration and carcinogenesis, with recent reports implicating dedifferentiated islet cells both as endocrine progenitors and as the cell(s) of origin...
7.
Moogk D, Hanley S, Ramunas J, Blaylock A, Skorepova J, Rosenberg L, et al.
Biotechnol Bioeng . 2007 Jan; 97(5):1138-47. PMID: 17243145
A means of expanding islet cell mass is urgently needed to supplement the limited availability of donor islets of Langerhans for transplant. Live cell imaging of human islets in culture...
8.
Hanley S, Liu S, Lipsett M, Castellarin M, Rosenberg L, Tchervenkov J, et al.
Transplantation . 2006 Sep; 82(6):813-8. PMID: 17006329
Background: Recent successes in islet transplantation highlight the importance of islet isolation by experienced centers and minimization of cell injury as crucial to the achievement of insulin independence. Islet injury...
9.
Lipsett M, Aikin R, Hanley S, Al-Maleek J, Laganiere S, Rosenburg L
Int J Biochem Cell Biol . 2006 Apr; 38(5-6):715-20. PMID: 16607698
Current therapies for type 1 diabetes, including fastidious blood glucose monitoring and multiple daily insulin injections, are not sufficient to prevent complications of the disease. Though pancreas and possibly islet...
10.
Lipsett M, Aikin R, Castellarin M, Hanley S, Jamal A, Laganiere S, et al.
Int J Biochem Cell Biol . 2005 Oct; 38(4):498-503. PMID: 16216541
Current therapies for type 1 diabetes, including fastidious blood glucose monitoring and multiple daily insulin injections, are not sufficient to prevent complications of the disease. Though pancreas and possibly islet...