Stephen H Wrzesinski
Overview
Explore the profile of Stephen H Wrzesinski including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
1241
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Wladis E, Wrzesinski S, Rothschild M, Adam A
Orbit
. 2022 Oct;
42(2):117-123.
PMID: 36214105
Purpose: Recently, several new therapies have emerged to address locally advanced cutaneous basal cell and squamous cell carcinomas. Given the constraints of the ocular adnexa and orbit, this review was...
2.
Roschewski M, Lionakis M, Sharman J, Roswarski J, Goy A, Monticelli M, et al.
Sci Immunol
. 2020 Jun;
5(48).
PMID: 32503877
Patients with severe COVID-19 have a hyperinflammatory immune response suggestive of macrophage activation. Bruton tyrosine kinase (BTK) regulates macrophage signaling and activation. Acalabrutinib, a selective BTK inhibitor, was administered off-label...
3.
Wrzesinski S, Fisher J, Ernstoff M
Exp Hematol Oncol
. 2013 Mar;
2(1):8.
PMID: 23497451
Among the dendritic cell (DC) subsets, plasmacytoid DC's (pDC) are thought to be important in the generation of both antiviral and antitumor responses. While pDC may be useful in developing...
4.
5.
Park J, Wrzesinski S, Stern E, Look M, Criscione J, Ragheb R, et al.
Nat Mater
. 2012 Jul;
11(10):895-905.
PMID: 22797827
The tumour microenvironment thwarts conventional immunotherapy through multiple immunologic mechanisms, such as the secretion of the transforming growth factor-β (TGF-β), which stunts local tumour immune responses. Therefore, high doses of...
6.
Wrzesinski S, Taddei T, Strazzabosco M
Clin Liver Dis
. 2011 Jun;
15(2):423-41, vii-x.
PMID: 21689622
Many potential systemic therapies are being investigated for the treatment of hepatocellular carcinoma (HCC). The incidence of this malignancy is rising sharply and the vast majority of patients present at...
7.
Flavell R, Sanjabi S, Wrzesinski S, Licona-Limon P
Nat Rev Immunol
. 2010 Jul;
10(8):554-67.
PMID: 20616810
Transforming growth factor-beta (TGFbeta) is an immunosuppressive cytokine produced by tumour cells and immune cells that can polarize many components of the immune system. This Review covers the effects of...
8.
Steenblock E, Wrzesinski S, Flavell R, Fahmy T
Expert Opin Biol Ther
. 2009 Apr;
9(4):451-64.
PMID: 19344282
Background: Recent findings on T cells and dendritic cells have elucidated principles that can be used for a bottom-up approach to engineering artificial antigen presentation on synthetic substrates. Objective/methods: To...
9.
Rabinovich P, Komarovskaya M, Wrzesinski S, Alderman J, Budak-Alpdogan T, Karpikov A, et al.
Hum Gene Ther
. 2008 Nov;
20(1):51-61.
PMID: 19025415
mRNA transfection is a useful approach for temporal cell reprogramming with minimal risk of transgene-mediated mutagenesis. We applied this to redirect lymphocyte cytotoxicity toward malignant cells. Using the chimeric immune...
10.
Wrzesinski S, Wan Y, Flavell R
Clin Cancer Res
. 2007 Sep;
13(18 Pt 1):5262-70.
PMID: 17875754
Immune homeostasis is a delicate balance between the immune defense against foreign pathogens and suppression of the immune system to maintain self-tolerance and prevent autoimmune disease. Maintenance of this balance...