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Stephen E Braun

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Articles 33
Citations 268
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Recent Articles
1.
Zenere G, Wu C, Midkiff C, Johnson N, Grice C, Wimley W, et al.
PLoS One . 2024 Aug; 19(8):e0293990. PMID: 39133676
Chimeric antigen receptor (CAR)-T cells have demonstrated clinical potential, but current receptors still need improvements to be successful against chronic HIV infection. In this study, we address some requirements of...
2.
Schulz M, Akerstrom V, Song K, Broyhill S, Li M, Lambert M, et al.
bioRxiv . 2024 Jun; PMID: 38826322
Rationale: TRPV4 channels are critical regulators of blood vascular function and have been shown to be dysregulated in many disease conditions in association with inflammation and tissue fibrosis. These are...
3.
Zenere G, Wu C, Midkiff C, Johnson N, Grice C, Wimley W, et al.
bioRxiv . 2023 Nov; PMID: 37961145
Chimeric antigen receptor (CAR)-T cells have demonstrated clinical potential, but current receptors still need improvements to be successful against chronic HIV infection. In this study, we address some requirements of...
4.
Casy W, Garza I, Chen X, Dong T, Hu Y, Kanchwala M, et al.
Genes (Basel) . 2023 Aug; 14(8). PMID: 37628711
The use of AAV capsid libraries coupled with various selection strategies has proven to be a remarkable approach for generating novel AAVs with enhanced and desired features. The inability to...
5.
Taghavi S, Abdullah S, Shaheen F, Packer J, Duchesne J, Braun S, et al.
Shock . 2023 Apr; 60(1):56-63. PMID: 37086080
Introduction: Endothelial glycocalyx damage occurs in numerous pathological conditions and results in endotheliopathy. Extracellular vesicles, including exosomes and microvesicles, isolated from adipose-derived mesenchymal stem cells (ASCs) have therapeutic potential in...
6.
Chandra P, Braun S, Maity S, Castorena-Gonzalez J, Kim H, Shaffer J, et al.
Viruses . 2023 Mar; 15(3). PMID: 36992502
Despite the suppression of human immunodeficiency virus (HIV) replication by combined antiretroviral therapy (cART), 50-60% of HIV-infected patients suffer from HIV-associated neurocognitive disorders (HAND). Studies are uncovering the role of...
7.
Izadpanah A, Daneshimehr F, Willingham K, Barabadi Z, Braun S, Dumont A, et al.
Front Oncol . 2022 Sep; 12:893820. PMID: 36046049
Increased vascularization, also known as neoangiogenesis, plays a major role in many cancers, including glioblastoma multiforme (GBM), by contributing to their aggressive growth and metastasis. Although anti-angiogenic therapies provide some...
8.
Jablon K, Akerstrom V, Li M, Braun S, Norton C, Castorena-Gonzalez J
Microcirculation . 2022 Jul; 30(2-3):e12778. PMID: 35879879
Objective: To develop an experimental method for routine isolation and short-term culture of primary lymphatic endothelial cells from specific collecting vessels. Methods: Lymphatic endothelial cell tubes (LECTs) were isolated from...
9.
Scheller S, Rashad Y, Saleh F, Willingham K, Reilich A, Lin D, et al.
Front Immunol . 2022 Apr; 13:821190. PMID: 35386712
Transplanting HIV-1 positive patients with hematopoietic stem cells homozygous for a 32 bp deletion in the chemokine receptor type 5 (CCR5) gene resulted in a loss of detectable HIV-1, suggesting...
10.
Johnson N, Alvarado A, Moffatt T, Edavettal J, Swaminathan T, Braun S
Mol Ther Methods Clin Dev . 2021 May; 21:451-465. PMID: 33981779
Three gene therapy strategies have received US Food and Drug Administration (FDA) approval; one includes HIV-1-based lentiviral vectors. These vectors incorporate features to provide long-term gene transfer and expression while...