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Asim B Abdel-Mageed

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Articles 81
Citations 2044
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Recent Articles
1.
Liu S, Rivero S, Zhang B, Shen K, Li Z, Niu T, et al.
J Natl Cancer Inst . 2024 Jun; 116(10):1598-1611. PMID: 38833676
Background: The role of Th17 cells in prostate cancer is not fully understood. The transcription factor BATF controls the differentiation of Th17 cells. Mice deficient in Batf do not produce...
2.
Chandra P, Braun S, Maity S, Castorena-Gonzalez J, Kim H, Shaffer J, et al.
Viruses . 2023 Mar; 15(3). PMID: 36992502
Despite the suppression of human immunodeficiency virus (HIV) replication by combined antiretroviral therapy (cART), 50-60% of HIV-infected patients suffer from HIV-associated neurocognitive disorders (HAND). Studies are uncovering the role of...
3.
Greenberg J, Kim H, Ahn M, Moustafa A, Zhou H, Barata P, et al.
Cancers (Basel) . 2022 Feb; 14(4). PMID: 35205655
Background: Tyrosine kinase inhibitors (TKI) were initially demonstrated as an efficacious treatment for renal cell carcinoma (RCC). However, after a median treatment length of 14 months, a vast majority of...
4.
Liu S, Zhang B, Rowan B, Jazwinski S, Abdel-Mageed A, Steele C, et al.
Front Mol Biosci . 2021 Jun; 8:696537. PMID: 34150854
Prostate cancer (PCa) is associated with advanced age, but how age contributes to prostate carcinogenesis remains unknown. The prostate-specific Pten conditional knockout mouse model closely imitates human PCa initiation and...
5.
Greenberg J, Kim H, Moustafa A, Datta A, Barata P, Boulares A, et al.
Sci Rep . 2021 May; 11(1):10200. PMID: 33986386
Renal Cell Carcinoma (RCC) is the most common form of kidney cancer, with clear cell RCC (ccRCC) representing about 85% of all RCC tumors. There are limited curable treatments available...
6.
Chandra P, Rutkai I, Kim H, Braun S, Abdel-Mageed A, Mondal D, et al.
Mol Neurobiol . 2021 Feb; 58(6):2974-2989. PMID: 33586027
Damage to the cerebral vascular endothelium is a critical initiating event in the development of HIV-1-associated neurocognitive disorders. To study the role of mitochondria in cerebral endothelial dysfunction, we investigated...
7.
Gur S, Alzweri L, Yilmaz-Oral D, Kaya-Sezginer E, Abdel-Mageed A, Dick B, et al.
Andrology . 2020 Jul; 8(6):1824-1833. PMID: 32672414
Background: Testosterone (T) deficiency is associated with erectile dysfunction (ED). The relaxant response of T on the corporal smooth muscle through a non-genomic pathway has been reported; however, the in...
8.
Liu S, Liu F, Zhang B, Yan P, Rowan B, Abdel-Mageed A, et al.
Prostate . 2020 May; 80(10):764-776. PMID: 32356608
Background: Aging is the most important risk factor for prostate cancer (PCa), but how age contributes to PCa is poorly understood. Aging is characterized by low-grade systemic inflammation (i.e., inflammaging)...
9.
Khurana N, Chandra P, Kim H, Abdel-Mageed A, Mondal D, Sikka S
Antioxidants (Basel) . 2020 Jan; 9(1). PMID: 31940946
Androgen receptor (AR) signaling is fundamental to prostate cancer (PC) progression, and hence, androgen deprivation therapy (ADT) remains a mainstay of treatment. However, augmented AR signaling via both full length...
10.
Gur S, Alzweri L, Yilmaz-Oral D, Kaya-Sezginer E, Abdel-Mageed A, Sikka S, et al.
Aging Male . 2019 Nov; 23(5):1088-1097. PMID: 31741421
Objective: To evaluate the effect of the I channel inhibitor, ivabradine on human corpus cavernosum (HCC) smooth muscle tone. Methods: HCC samples were obtained from erectile dysfunction(ED) patients ( = ...