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Stephen Doran

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Articles 23
Citations 333
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Recent Articles
1.
Gorry C, Daly M, Barrett R, Finnigan K, Smith A, Doran S, et al.
Appl Health Econ Health Policy . 2024 Aug; 22(6):771-781. PMID: 39133443
The Health Service Executive, responsible for operating the Irish health service, has introduced health technology management (HTM) initiatives to manage expenditure on medicines. One such approach is managed access protocols...
2.
Laudette M, Lindbom M, Arif M, Cinato M, Ruiz M, Doran S, et al.
Cardiovasc Res . 2023 Mar; 119(7):1537-1552. PMID: 36880401
Aims: Pro-protein convertase subtilisin-kexin type 9 (PCSK9), which is expressed mainly in the liver and at low levels in the heart, regulates cholesterol levels by directing low-density lipoprotein receptors to...
3.
Andersson L, Cinato M, Mardani I, Miljanovic A, Arif M, Koh A, et al.
Eur Heart J . 2021 Jul; 42(43):4481-4492. PMID: 34297830
Aims: Cardiac injury and remodelling are associated with the rearrangement of cardiac lipids. Glycosphingolipids are membrane lipids that are important for cellular structure and function, and cardiac dysfunction is a...
4.
Alishlash A, Sapkota M, Ahmad I, Maclin K, Ahmed N, Molyvdas A, et al.
Redox Biol . 2021 May; 44:102009. PMID: 34044323
Triggering factors of Acute Chest Syndrome (ACS) is a leading cause of death in patients with Sickle Cell Disease (SCD) and targeted therapies are limited. Chlorine (Cl) inhalation happens frequently,...
5.
Arif M, Klevstig M, Benfeitas R, Doran S, Turkez H, Uhlen M, et al.
Elife . 2021 May; 10. PMID: 33972017
Myocardial infarction (MI) promotes a range of systemic effects, many of which are unknown. Here, we investigated the alterations associated with MI progression in heart and other metabolically active tissues...
6.
Norris B, Smith A, Doran S, Barry M
Pharmacoepidemiol Drug Saf . 2021 Apr; 30(8):1003-1011. PMID: 33840133
Purpose: Significant increases in opioid utilisation have been reported in many countries in recent decades. This study investigated strong opioid prescribing in Irish General Medical Services (GMS) patients over a...
7.
Doran S, Arif M, Lam S, Bayraktar A, Turkez H, Uhlen M, et al.
Brief Bioinform . 2021 Mar; 22(5). PMID: 33725119
The development and progression of cardiovascular disease (CVD) can mainly be attributed to the narrowing of blood vessels caused by atherosclerosis and thrombosis, which induces organ damage that will result...
8.
Kennedy C, Smith A, Doran S, Barry M
Br J Clin Pharmacol . 2020 May; 87(2):406-413. PMID: 32470158
Aims: Entresto (sacubitril/valsartan) is used to treat symptomatic chronic heart failure with reduced ejection fraction. Given its high potential budget impact, the Health Services Executive introduced a reimbursement application system...
9.
Doran S
Linacre Q . 2020 May; 86(4):327-334. PMID: 32431425
Summary: While organ donation is an act of love, the donation process can be distraction from the care of the dying patient, who may be treated differently than other dying...
10.
Smith A, Doran S, Daly M, Kennedy C, Barry M
Appl Health Econ Health Policy . 2020 May; 19(1):133-140. PMID: 32430656
Background: The lidocaine 5% medicated plaster, Versatis, has one therapeutic indication listed on the Summary of Product Characteristics-symptomatic relief of post-herpetic neuralgia (PHN) in adults. Increased expenditure on Versatis suggests...