Stephanie Wunderlich
Overview
Explore the profile of Stephanie Wunderlich including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
491
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0
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Recent Articles
1.
Heseding H, Jahn K, Brandl B, Haase A, Shum I, Kohrn T, et al.
Stem Cell Res
. 2023 Jun;
71:103143.
PMID: 37343429
Prader-Willi syndrome (PWS) is a neurodevelopmental disorder caused by loss of paternal expression of imprinted genes on chromosome 15q11-q13. We established a human induced pluripotent stem cell line (hiPSC), ZIPi021-A,...
2.
Wunderlich S, Haase A, Merkert S, Jahn K, Deest M, Frieling H, et al.
Mol Ther Methods Clin Dev
. 2022 Jul;
26:84-94.
PMID: 35795779
Drug-inducible suicide systems may help to minimize risks of human induced pluripotent stem cell (hiPSC) therapies. Recent research challenged the usefulness of such systems since rare drug-resistant subclones were observed....
3.
Reprogramming enriches for somatic cell clones with small-scale mutations in cancer-associated genes
Kosanke M, Osetek K, Haase A, Wiehlmann L, Davenport C, Schwarzer A, et al.
Mol Ther
. 2021 Apr;
29(8):2535-2553.
PMID: 33831558
Cellular therapies based on induced pluripotent stem cells (iPSCs) come out of age and an increasing number of clinical trials applying iPSC-based transplants are ongoing or in preparation. Recent studies,...
4.
Benito-Kwiecinski S, Giandomenico S, Sutcliffe M, Riis E, Freire-Pritchett P, Kelava I, et al.
Cell
. 2021 Mar;
184(8):2084-2102.e19.
PMID: 33765444
The human brain has undergone rapid expansion since humans diverged from other great apes, but the mechanism of this human-specific enlargement is still unknown. Here, we use cerebral organoids derived...
5.
Nowak-Imialek M, Wunderlich S, Herrmann D, Breitschuh-Leibling S, Gohring G, Petersen B, et al.
Cell Reprogram
. 2020 May;
22(3):118-133.
PMID: 32429746
Chimeric pigs harboring organs derived from human stem cells are promising for patient-specific regenerative therapies. Induced pluripotent stem cells (iPSCs) can contribute to all cell types of the fetus, including...
6.
Lipus A, Janosz E, Ackermann M, Hetzel M, Dahlke J, Buchegger T, et al.
Int J Mol Sci
. 2020 Apr;
21(7).
PMID: 32260086
Induced pluripotent stem cells (iPSCs) offer great promise for the field of regenerative medicine, and iPSC-derived cells have already been applied in clinical practice. However, potential contamination of effector cells...
7.
Halloin C, Schwanke K, Lobel W, Franke A, Szepes M, Biswanath S, et al.
Stem Cell Reports
. 2019 Oct;
13(4):775.
PMID: 31597111
No abstract available.
8.
Halloin C, Schwanke K, Lobel W, Franke A, Szepes M, Biswanath S, et al.
Stem Cell Reports
. 2019 Jul;
13(2):366-379.
PMID: 31353227
Aiming at clinical translation, robust directed differentiation of human pluripotent stem cells (hPSCs), preferentially in chemically defined conditions, is a key requirement. Here, feasibility of suspension culture based hPSC-cardiomyocyte (hPSC-CM)...
9.
Malysheva S, Wunderlich S, Haase A, Gohring G, Martin U, Merkert S
Stem Cell Res
. 2018 Jun;
30:117-121.
PMID: 29852468
Caudal-type homeobox 2 (CDX2) transcription factor is an important marker for early trophoblast lineages and intestinal epithelium. Due to its nuclear expression the immunostaining and sorting of viable CDX2 cells...
10.
Merkert S, Wunderlich S, Bednarski C, Beier J, Haase A, Dreyer A, et al.
Stem Cell Reports
. 2014 Mar;
2(1):107-18.
PMID: 24678453
Genetic engineering of human induced pluripotent stem cells (hiPSCs) via customized designer nucleases has been shown to be significantly more efficient than conventional gene targeting, but still typically depends on...