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Stephanie Totten

Explore the profile of Stephanie Totten including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 131
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Recent Articles
11.
Cepeda Canedo E, Totten S, Ahn R, Savage P, MacNeil D, Hudson J, et al.
JCI Insight . 2021 Jan; 6(4). PMID: 33470989
Triple-negative breast cancers (TNBCs) lack effective targeted therapies, and cytotoxic chemotherapies remain the standard of care for this subtype. Owing to their increased genomic instability, poly (ADP-ribose) polymerase (PARP) inhibitors...
12.
Maloney E, Wang Y, Vohra R, Son H, Whang S, Khokhlova T, et al.
World J Gastroenterol . 2020 Mar; 26(9):904-917. PMID: 32206002
Background: The robust fibroinflammatory stroma characteristic of pancreatic ductal adenocarcinoma (PDA) impedes effective drug delivery. Pulsed focused ultrasound (pFUS) can disrupt this stroma and has improved survival in an early...
13.
Totten S, Fraser R
Med Educ . 2018 Oct; 52(11):1186. PMID: 30345669
No abstract available.
14.
Ahn R, Sabourin V, Bolt A, Hebert S, Totten S, De Jay N, et al.
Nat Commun . 2017 Mar; 8:14638. PMID: 28276425
Tyrosine kinase signalling within cancer cells is central to the establishment of an immunosuppressive microenvironment. Although tyrosine kinase inhibitors act, in part, to augment adaptive immunity, the increased heterogeneity and...
15.
Chatterjee A, Caballero-Franco C, Bakker D, Totten S, Jardim A
J Biol Chem . 2015 Sep; 290(42):25579-94. PMID: 26324713
Enterohemorrhagic Escherichia coli is a causative agent of gastrointestinal and diarrheal diseases. Pathogenesis associated with enterohemorrhagic E. coli involves direct delivery of virulence factors from the bacteria into epithelial cell...
16.
Czikk M, Totten S, Hammond R, Richardson B
Reprod Sci . 2014 Apr; 22(3):367-76. PMID: 24700051
We have determined the change in immunoreactivity (IR) for microtubule-associated protein 2 (MAP-2) and synaptophysin (SYN) as markers for dendritic and presynaptic nerve development, respectively, in the ovine fetal brain...
17.
Rotermann M, Langlois K, Severini A, Totten S
Health Rep . 2013 Nov; 24(4):10-5. PMID: 24258059
Background: Chlamydia, caused by Chlamydia trachomatis, and genital herpes, caused by simplex virus type 2 (HSV-2), are common sexually transmitted infections. Their prevalence has been estimated in selected populations, but...
18.
Jiang Y, Brassard P, Severini A, Mao Y, Li Y, Laroche J, et al.
Infect Agent Cancer . 2013 Jul; 8(1):25. PMID: 23816397
Introduction: Certain types of the Human Papillomavirus (HPV) are sexually transmitted and highly associated with development of cervical dysplasia and cervical cancer but the distribution of HPV infection in the...
19.
Rocha E, Totten S, Hammond R, Han V, Richardson B
Am J Obstet Gynecol . 2004 Sep; 191(2):497-506. PMID: 15343227
Objective: The purpose of this study was to determine the immunoreactivity of selected structural proteins in the preterm and near-term ovine fetal brain and the response to intermittent umbilical cord...