Stephanie N Oprescu
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Explore the profile of Stephanie N Oprescu including associated specialties, affiliations and a list of published articles.
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22
Citations
386
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Recent Articles
1.
Yue F, Gu L, Qiu J, Oprescu S, Beckett L, Ellis J, et al.
EMBO J
. 2025 Mar;
PMID: 40065099
During homeostasis and regeneration, satellite cells, the resident stem cells of skeletal muscle, have distinct metabolic requirements for fate transitions between quiescence, proliferation and differentiation. However, the contribution of distinct...
2.
Meyer-Schuman R, Cale A, Pierluissi J, Jonatzke K, Park Y, Lenk G, et al.
HGG Adv
. 2024 Jul;
5(3):100324.
PMID: 38956874
Aminoacyl-tRNA synthetases (ARSs) are ubiquitously expressed, essential enzymes that complete the first step of protein translation: ligation of amino acids to cognate tRNAs. Genes encoding ARSs have been implicated in...
3.
Xu H, Le V, Oprescu S, Kuang S
Curr Top Dev Biol
. 2024 Apr;
158:221-238.
PMID: 38670707
The skeletal muscle is well known for its remarkable ability to regenerate after injuries. The regeneration is a complex and dynamic process that involves muscle stem cells (also called muscle...
4.
Meyer-Schuman R, Cale A, Pierluissi J, Jonatzke K, Park Y, Lenk G, et al.
bioRxiv
. 2024 Apr;
PMID: 38585737
Aminoacyl-tRNA synthetases (ARSs) are ubiquitously expressed, essential enzymes that complete the first step of protein translation: ligation of amino acids to cognate tRNAs. Genes encoding ARSs have been implicated in...
5.
Kim K, Oprescu S, Snyder M, Kim A, Jia Z, Yue F, et al.
Cell Rep
. 2023 Oct;
42(11):113329.
PMID: 37883229
Development is regulated by various factors, including protein methylation status. While PRMT5 is well known for its roles in oncogenesis by mediating symmetric di-methylation of arginine, its role in normal...
6.
Oprescu S, Baumann N, Chen X, Sun Q, Zhao Y, Yue F, et al.
Skelet Muscle
. 2023 Sep;
13(1):15.
PMID: 37705115
Transcription factors (TFs) play key roles in regulating differentiation and function of stem cells, including muscle satellite cells (MuSCs), a resident stem cell population responsible for postnatal regeneration of the...
7.
Kim K, Jia Z, Snyder M, Chen J, Qiu J, Oprescu S, et al.
EMBO Rep
. 2023 Jun;
24(8):e57306.
PMID: 37334900
Skeletal muscle plays a key role in systemic energy homeostasis besides its contractile function, but what links these functions is poorly defined. Protein Arginine Methyl Transferase 5 (PRMT5) is a...
8.
Oprescu S, Baumann N, Chen X, Sun Q, Zhao Y, Yue F, et al.
bioRxiv
. 2023 Apr;
PMID: 37034612
Transcription factors (TFs) play key roles in regulating the differentiation and function of stem cells, including muscle satellite cells (MuSCs), a resident stem cell population responsible for postnatal regeneration of...
9.
Chang Y, Syahirah R, Oprescu S, Wang X, Jung J, Cooper S, et al.
Biomaterials
. 2022 May;
285:121569.
PMID: 35567999
Human hematopoietic stem cells (HSCs), which arise from aorta-gonad-mesonephros (AGM), are widely used to treat blood diseases and cancers. However, a technique for their robust generation in vitro is still...
10.
Jia Z, Chen X, Chen J, Zhang L, Oprescu S, Luo N, et al.
Clin Transl Med
. 2022 Feb;
12(2):e665.
PMID: 35184387
Propionate is a gut microbial metabolite that has been reported to have controversial effects on metabolic health. Here we show that propionate is activated by acyl-CoA synthetase short-chain family member...