Stephanie M Cabarcas
Overview
Explore the profile of Stephanie M Cabarcas including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
351
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0
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Recent Articles
1.
Cryptotanshinone targets tumor-initiating cells through down-regulation of stemness genes expression
Zhang Y, Cabarcas S, Zheng J, Sun L, Mathews L, Zhang X, et al.
Oncol Lett
. 2016 Jun;
11(6):3803-3812.
PMID: 27313698
Recent evidence indicates that tumor-initiating cells (TICs), also called cancer stem cells (CSCs), are responsible for tumor initiation and progression, therefore representing an important cell population that may be used...
2.
Sun L, Mathews L, Cabarcas S, Zhang X, Yang A, Zhang Y, et al.
Stem Cells
. 2013 Apr;
31(8):1454-66.
PMID: 23592398
Pancreatic cancer is the fourth leading cause of cancer-related mortality in the world. Pancreatic cancer can be localized, locally advanced, or metastatic. The median 1- and 5-year survival rates are...
3.
Cabarcas S, Sun L, Mathews L, Thomas S, Zhang X, Farrar W
Pancreas
. 2013 Mar;
42(5):861-70.
PMID: 23462327
Objective: Pancreatic cancer is a leading cancer type and its molecular pathology is poorly understood. The only potentially curative therapeutic option available is complete surgical resection; however, this is inadequate...
4.
Kang M, Baker A, Dextras C, Cabarcas S, Young M, Colburn N
Genes Cancer
. 2012 Aug;
3(1):37-50.
PMID: 22893789
The transcription factor AP-1 (activator protein-1) regulates a number of genes that drive tumor promotion and progression. While basal levels of AP-1 activity are important for normal cell proliferation and...
5.
Cabarcas S, Thomas S, Zhang X, Cherry J, Sebastian T, Yerramilli S, et al.
Genomics
. 2011 Dec;
99(2):108-17.
PMID: 22206861
TICs are characterized by their ability to self-renew, differentiate and initiate tumor formation. miRNAs are small noncoding RNAs that bind to mRNAs resulting in regulation of gene expression and biological...
6.
Cabarcas S, Mathews L, Farrar W
Int J Cancer
. 2011 Jul;
129(10):2315-27.
PMID: 21792897
The niche is the environment in which stem cells reside and is responsible for the maintenance of unique stem cell properties such as self-renewal and an undifferentiated state. The heterogeneous...
7.
Mathews L, Cabarcas S, Hurt E, Zhang X, Jaffee E, Farrar W
Pancreas
. 2011 Jun;
40(5):730-9.
PMID: 21633318
Objective: Pancreatic cancer was the fourth leading cause of cancer death in the United States in 2010. Recurrence of disease after resection occurs because of neoplastic cell survival. To better...
8.
Crea F, Hurt E, Mathews L, Cabarcas S, Sun L, Marquez V, et al.
Mol Cancer
. 2011 Apr;
10:40.
PMID: 21501485
Background: Polycomb repressive complex 2 (PRC2) mediates gene silencing through histone H3K27 methylation. PRC2 components are over-expressed in metastatic prostate cancer (PC), and are required for cancer stem cell (CSC)...
9.
Mathews L, Cabarcas S, Farrar W
Cancer Metastasis Rev
. 2011 Feb;
30(2):185-97.
PMID: 21340664
The existence of "tumor-initiating cells" (TICs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety...