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Stephanie Duhamel

Explore the profile of Stephanie Duhamel including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 301
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Goyette M, Duhamel S, Aubert L, Pelletier A, Savage P, Thibault M, et al.
Cell Rep . 2023 Dec; 42(12):113604. PMID: 38100352
No abstract available.
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Pelletier B, Duhamel S, Tambutet G, Jarvis S, Cleroux P, David M, et al.
ACS Chem Biol . 2023 Apr; 18(5):1039-1046. PMID: 37097827
p21 (p21) is a universal cyclin-dependent kinase (CDK) inhibitor that halts cell proliferation and tumor growth by multiple mechanisms. The expression of p21 is often downregulated in cancer cells as...
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Zaoui K, Duhamel S
Eur J Cell Biol . 2023 Mar; 102(2):151313. PMID: 36996579
The small GTPase RhoB is distinguished from other Rho proteins by its unique subcellular localization in endosomes, multivesicular bodies, and nucleus. Despite high sequence homology with RhoA and RhoC, RhoB...
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Gresseau L, Roy M, Duhamel S, Annabi B
Cancers (Basel) . 2022 Dec; 14(23). PMID: 36497426
: Three-dimensional in vitro neurospheres cultures recapitulate stemness features associated with poor clinical outcome in glioblastoma patients. They are commonly used to address brain cancer stem cell (CSC) signal transducing...
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Kassouri C, Rodriguez Torres S, Gonzalez Suarez N, Duhamel S, Annabi B
Cancers (Basel) . 2022 Oct; 14(20). PMID: 36291849
Background: The promyelocytic leukemia cell differentiation process enables recapitulation of the polarized M1 or M2 macrophage-like phenotype with inflammatory and immune-suppressive properties. While evidence supports the anti-inflammatory effect of dietary-derived...
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Stern Y, Al-Ghabkari A, Monast A, Fiset B, Aboualizadeh F, Yao Z, et al.
Cell Mol Life Sci . 2022 Mar; 79(3):178. PMID: 35249128
Receptor tyrosine kinases (RTKs) are recognized as targets of precision medicine in human cancer upon their gene amplification or constitutive activation, resulting in increased downstream signal complexity including heterotypic crosstalk...
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Sung V, Knight J, Johnson R, Stern Y, Saleh S, Savage P, et al.
NPJ Breast Cancer . 2021 Mar; 7(1):36. PMID: 33772015
Triple-negative breast cancer (TNBC) is a heterogeneous disease that lacks both effective patient stratification strategies and therapeutic targets. Whilst elevated levels of the MET receptor tyrosine kinase are associated with...
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Zaoui K, Duhamel S
Bio Protoc . 2021 Mar; 10(9):e3609. PMID: 33659574
The Ras homologous protein (Rho) GTPase subfamily, including RhoA, RhoB, and RhoC are small molecules (~21 kDa) that act as molecular switches in a wide range of signaling pathways to...
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Duhamel S, Zaoui K
Bio Protoc . 2021 Mar; 10(20):e3794. PMID: 33659448
Endocytic trafficking and recycling are fundamental cellular processes that control essential functions such as signaling protein complexes transport and membrane identity. The small GTPase Rabs are indispensable component of the...