Morag Park
Overview
Explore the profile of Morag Park including associated specialties, affiliations and a list of published articles.
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Articles
181
Citations
7310
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Recent Articles
1.
Minarrieta L, Annis M, Audet-Delage Y, Kuasne H, Pacis A, St-Louis C, et al.
Sci Adv
. 2024 Nov;
10(45):eadm8212.
PMID: 39504368
Mitochondrial dynamics orchestrate many essential cellular functions, including metabolism, which is instrumental in promoting cancer growth and metastatic progression. However, how mitochondrial dynamics influences metastatic progression remains poorly understood. Here,...
2.
Gu Y, Taifour T, Bui T, Zuo D, Pacis A, Poirier A, et al.
Nat Commun
. 2024 Oct;
15(1):9174.
PMID: 39448577
Recurrent breast cancers often develop resistance to standard-of-care therapies. Identifying targetable factors contributing to cancer recurrence remains the rate-limiting step in improving long-term outcomes. In this study, we identify tumor...
3.
Dickinson K, Sharma A, Agnihotram R, Altuntur S, Park M, Meterissian S, et al.
JAMA Netw Open
. 2024 Sep;
7(9):e2431722.
PMID: 39235812
Importance: Metastatic breast cancer (MBC) poses a substantial clinical challenge despite advancements in diagnosis and treatment. While tissue biopsies offer a static snapshot of disease, liquid biopsy-through detection of circulating...
4.
Elkholi I, Robert A, Malouf C, Kuasne H, Drapela S, MacLeod G, et al.
bioRxiv
. 2024 Aug;
PMID: 39211165
Statement Of Significance: We reveal that dormancy-prone breast cancer cells depend on the class III PI3K to mediate a constant peripheral lysosomal positioning and mTORC1 hyperactivity. Targeting this pathway might...
5.
Khalil A, Smits D, Haughton P, Koorman T, Jansen K, Verhagen M, et al.
Nat Commun
. 2024 Jun;
15(1):4866.
PMID: 38849373
Dense and aligned Collagen I fibers are associated with collective cancer invasion led by protrusive tumor cells, leader cells. In some breast tumors, a population of cancer cells (basal-like cells)...
6.
Cao X, Fang T, Chen M, Ning T, Li J, Siegel P, et al.
Biomaterials
. 2024 Apr;
309:122582.
PMID: 38678699
Cold atmospheric plasma (CAP) is a unique form of physical plasma that has shown great potential for cancer therapy. CAP uses ionized gas to induce lethal oxidative stress on cancer...
7.
Kuzmin E, Baker T, Lesluyes T, Monlong J, Abe K, Coelho P, et al.
Cell Rep
. 2024 Mar;
43(4):113988.
PMID: 38517886
The basal breast cancer subtype is enriched for triple-negative breast cancer (TNBC) and displays consistent large chromosomal deletions. Here, we characterize evolution and maintenance of chromosome 4p (chr4p) loss in...
8.
Al-Ghabkari A, Huang B, Park M
Cells
. 2024 Feb;
13(3.
PMID: 38334610
Brain tumors represent a heterogeneous group of neoplasms characterized by a high degree of aggressiveness and a poor prognosis. Despite recent therapeutic advances, the treatment of brain tumors, including glioblastoma...
9.
Zhu X, Fu Z, Dutchak K, Arabzadeh A, Milette S, Steinberger J, et al.
Cancer Res
. 2024 Jan;
84(8):1333-1351.
PMID: 38277141
Significance: The combination of cytostatic CDK4/6 and BRD4 inhibitors induces senescent cancer cells that are primed for activation of ferroptotic cell death by targeting GPX4, providing an effective strategy for...
10.
Dankner M, Maritan S, Priego N, Kruck G, Nkili-Meyong A, Nadaf J, et al.
Neuro Oncol
. 2024 Jan;
26(6):1052-1066.
PMID: 38271182
Background: Compared to minimally invasive brain metastases (MI BrM), highly invasive (HI) lesions form abundant contacts with cells in the peritumoral brain parenchyma and are associated with poor prognosis. Reactive...