Stephanie A Booth
Overview
Explore the profile of Stephanie A Booth including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
53
Citations
1325
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Slota J, Lamoureux L, Frost K, Sajesh B, Booth S
Nat Commun
. 2024 Nov;
15(1):10174.
PMID: 39580485
Understanding why certain neurons are more sensitive to dysfunction and death caused by misfolded proteins could provide therapeutically relevant insights into neurodegenerative disorders. Here, we harnessed single-cell transcriptomics to examine...
2.
Myskiw J, Bailey-Elkin B, Avery K, Barria M, Ritchie D, Cohen M, et al.
Sci Rep
. 2024 Nov;
14(1):27867.
PMID: 39537719
Variably Protease Sensitive Prionopathy (VPSPr) is a rare human prion disease that, like Creutzfeldt-Jakob disease (CJD), results in the deposition of abnormally folded prion protein aggregates in the brain and...
3.
Mehra S, Bourkas M, Kaczmarczyk L, Stuart E, Arshad H, Griffin J, et al.
J Clin Invest
. 2024 Aug;
134(15.
PMID: 39087478
Most cases of human prion disease arise due to spontaneous misfolding of WT or mutant prion protein, yet recapitulating this event in animal models has proven challenging. It remains unclear...
4.
Slota J, Wang X, Lusansky D, Medina S, Booth S
Prion
. 2023 May;
17(1):116-132.
PMID: 37131335
Prions are misfolded proteins that accumulate within the brain in association with a rare group of fatal and infectious neurological disorders in humans and animals. A current challenge to research...
5.
Myskiw J, Lamoureux L, Peterson A, Knox D, Jansen G, Coulthart M, et al.
Lab Invest
. 2023 Mar;
103(3):100029.
PMID: 36925197
Creutzfeldt-Jakob disease (CJD) comprises a group of transmissible neurodegenerative diseases with vast phenotypic diversity. Sporadic CJD heterogeneity is predominantly influenced by the genotype at codon 129 of the prion-encoding gene...
6.
Tailor N, Warner B, Griffin B, Tierney K, Moffat E, Frost K, et al.
Viruses
. 2023 Jan;
15(1).
PMID: 36680125
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of coronavirus disease 2019 (COVID-19) that has caused a pandemic with millions of human infections. There continues to be...
7.
Slota J, Sajesh B, Frost K, Medina S, Booth S
Acta Neuropathol Commun
. 2022 Nov;
10(1):161.
PMID: 36352465
Prion diseases are neurodegenerative disorders with long asymptomatic incubation periods, followed by a rapid progression of cognitive and functional decline culminating in death. The complexity of intercellular interactions in the...
8.
Lamoureux L, Sajesh B, Slota J, Medina S, Mayor M, Frost K, et al.
Viruses
. 2022 Jun;
14(6).
PMID: 35746689
The numerous neurological syndromes associated with COVID-19 implicate an effect of viral pathogenesis on neuronal function, yet reports of direct SARS-CoV-2 infection in the brain are conflicting. We used a...
9.
Slota J, Medina S, Frost K, Booth S
Front Neurosci
. 2022 Jun;
16:918811.
PMID: 35651626
Progressive dysfunction and loss of neurons ultimately culminates in the symptoms and eventual fatality of prion disease, yet the pathways and mechanisms that lead to neuronal degeneration remain elusive. Here,...
10.
Nemani S, Myskiw J, Lamoureux L, Booth S, Sim V
Viruses
. 2020 Dec;
12(12).
PMID: 33348562
The majority of human prion diseases are sporadic, but acquired disease can occur, as seen with variant Creutzfeldt-Jakob disease (vCJD) following consumption of bovine spongiform encephalopathy (BSE). With increasing rates...