Stephane Flibotte
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Explore the profile of Stephane Flibotte including associated specialties, affiliations and a list of published articles.
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85
Citations
1966
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Recent Articles
21.
Berndt A, Othonos K, Lian T, Flibotte S, Miao M, Bhuiyan S, et al.
Elife
. 2020 Oct;
9.
PMID: 33124981
Retrograde BMP signaling and canonical pMad/Medea-mediated transcription regulate diverse target genes across subsets of efferent neurons, to differentiate neuropeptidergic neurons and promote motor neuron terminal maturation. How a common BMP...
22.
Trivedi P, Bartlett J, Mercer A, Slade L, Surette M, Ballabio A, et al.
Biochim Biophys Acta Mol Basis Dis
. 2020 May;
1866(10):165832.
PMID: 32437957
Glucolipotoxicity following nutrient overload causes cardiomyocyte injury by inhibiting TFEB and suppressing lysosomal function. We ascertained whether in addition to the amount, the type of fatty acids (FAs) and duration...
23.
Ye F, Hamza A, Singh T, Flibotte S, Hieter P, ONeil N
Genetics
. 2020 May;
215(3):609-621.
PMID: 32414869
New anticancer therapeutics require extensive characterization to identify endogenous and exogenous factors affecting efficacy, to measure toxicity and mutagenicity, and to determine genotypes that result in therapeutic sensitivity or resistance....
24.
Li X, Itani O, Haataja L, Dumas K, Yang J, Cha J, et al.
Sci Adv
. 2019 Dec;
5(12):eaax0292.
PMID: 31840061
The mechanistic basis for the biogenesis of peptide hormones and growth factors is poorly understood. Here, we show that the conserved endoplasmic reticulum membrane translocon-associated protein α (TRAPα), also known...
25.
Puri K, Lal N, Shang R, Ghosh S, Flibotte S, Dyer R, et al.
J Am Heart Assoc
. 2019 Nov;
8(21):e014022.
PMID: 31665961
Background Fatty acid (FA) provision to the heart is from cardiomyocyte and adipose depots, plus lipoprotein lipase action. We tested how a graded reduction in insulin impacts the source of...
26.
Wolfe G, Tong V, Povse E, Merritt D, Stegeman G, Flibotte S, et al.
eNeuro
. 2019 Aug;
6(4).
PMID: 31371455
Associative learning and sensory integration are two behavioral processes that involve the sensation and processing of stimuli followed by an altered behavioral response to these stimuli, with learning requiring memory...
27.
Wang F, Pulinilkunnil T, Flibotte S, Nislow C, Vlodavsky I, Hussein B, et al.
J Mol Cell Cardiol
. 2019 Apr;
131:29-40.
PMID: 31004678
Although cancer cells use heparanase for tumor metastasis, favourable effects of heparanase have been reported in the management of Alzheimer's disease and diabetes. Indeed, we previously established a protective function...
28.
Billmyre K, Doebley A, Spichal M, Heestand B, Belicard T, Sato-Carlton A, et al.
PLoS Genet
. 2019 Mar;
15(3):e1008004.
PMID: 30921322
Germ cell immortality, or transgenerational maintenance of the germ line, could be promoted by mechanisms that could occur in either mitotic or meiotic germ cells. Here we report for the...
29.
Tigchelaar S, Gupta R, Shannon C, Streijger F, Sinha S, Flibotte S, et al.
J Neurotrauma
. 2019 Mar;
36(15):2358-2371.
PMID: 30827169
Spinal cord injury (SCI) is a devastating condition with variability in injury mechanisms and neurologic recovery. Spinal cord impairment after SCI is measured and classified by a widely accepted standard...
30.
Vuilleumier R, Lian T, Flibotte S, Khan Z, Fuchs A, Pyrowolakis G, et al.
Nucleic Acids Res
. 2018 Nov;
47(2):679-699.
PMID: 30476189
Retrograde Bone Morphogenetic Protein (BMP) signaling in neurons is essential for the differentiation and synaptic function of many neuronal subtypes. BMP signaling regulates these processes via Smad transcription factor activity,...