Stephane Flibotte
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Explore the profile of Stephane Flibotte including associated specialties, affiliations and a list of published articles.
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85
Citations
1966
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Recent Articles
11.
Skovso S, Panzhinskiy E, Kolic J, Cen H, Dionne D, Dai X, et al.
Nat Commun
. 2022 Feb;
13(1):735.
PMID: 35136059
Insulin receptor (Insr) protein is present at higher levels in pancreatic β-cells than in most other tissues, but the consequences of β-cell insulin resistance remain enigmatic. Here, we use an...
12.
Flibotte S, Edgley M, Au V, Moerman D
MicroPubl Biol
. 2021 Dec;
2021.
PMID: 34909608
We used whole-genome sequencing (WGS) data from a strain homozygous for the reciprocal translocation to identify its breakpoints molecularly. The translocation structure is fairly straightforward, with only minor secondary rearrangement...
13.
Edgley M, Flibotte S, Moerman D
MicroPubl Biol
. 2021 Nov;
2021.
PMID: 34746683
We used whole-genome sequencing (WGS) data from a number of balanced lethal strains in to show that the crossover suppressor is an inversion. The rearrangement is complex, with a large...
14.
Wang S, Mautner V, Buchert R, Flibotte S, Suppa P, Friedman J, et al.
Orphanet J Rare Dis
. 2021 Nov;
16(1):462.
PMID: 34727946
Objective: Neurofibromatosis 1 (NF1) is a rare autosomal dominant disease that causes the dysregulated growth of Schwann cells. Most reported studies of brain morphology in NF1 patients have included only...
15.
Chegounian P, Flibotte S, Peru K, Headley J, McMartin D, Gramlich B, et al.
Microorganisms
. 2021 Oct;
9(10).
PMID: 34683445
Naphthenic acid fraction compounds (NAFCs) are highly recalcitrant constituents of oil sands tailings. Although some microorganisms in the tailings can individually and synergistically metabolize NAFCs, the biochemical mechanisms that underpin...
16.
Li-Leger E, Feichtinger R, Flibotte S, Holzkamp H, Schnabel R, Moerman D
G3 (Bethesda)
. 2021 Sep;
11(12).
PMID: 34550348
It has been estimated that 15%-30% of the ∼20,000 genes in C. elegans are essential, yet many of these genes remain to be identified or characterized. With the goal of...
17.
Wang S, Flibotte S, Camunas-Soler J, MacDonald P, Johnson J
Can J Diabetes
. 2021 May;
45(8):775-784.e2.
PMID: 34052132
Objectives: Type 1 diabetes is characterized by the autoimmune destruction of insulin-secreting beta cells. Genetic variants upstream at the insulin (INS) locus contribute to ∼10% of type 1 diabetes heritable...
18.
Hosseini-Farahabadi S, Baradaran-Heravi A, Zimmerman C, Choi K, Flibotte S, Roberge M
PLoS Biol
. 2021 May;
19(5):e3001221.
PMID: 33939688
Premature termination codons (PTC) cause over 10% of genetic disease cases. Some aminoglycosides that bind to the ribosome decoding center can induce PTC readthrough and restore low levels of full-length...
19.
Wang X, Vlok M, Flibotte S, Jan E
Viruses
. 2021 Apr;
13(3).
PMID: 33802878
The dicistrovirus intergenic region internal ribosome entry site (IGR IRES) uses an unprecedented, streamlined mechanism whereby the IRES adopts a triple-pseudoknot (PK) structure to directly bind to the conserved core...
20.
Itani O, Zhong X, Tang X, Scott B, Yan J, Flibotte S, et al.
Curr Biol
. 2020 Nov;
31(1):128-137.e5.
PMID: 33157031
The translation machinery is composed of a myriad of proteins and RNAs whose levels must be coordinated to efficiently produce proteins without wasting energy or substrate. However, protein synthesis is...