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Stephane Emiliani

Explore the profile of Stephane Emiliani including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 2708
Followers 0
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Recent Articles
1.
Konan S, Segeral E, Bejjani F, Bendoumou M, Ait Said M, Gallois-Montbrun S, et al.
Retrovirology . 2024 Apr; 21(1):9. PMID: 38689286
No abstract available.
2.
Ait Said M, Bejjani F, Abdouni A, Segeral E, Emiliani S
Proc Natl Acad Sci U S A . 2023 Nov; 120(49):e2313356120. PMID: 38015843
Postintegration transcriptional silencing of HIV-1 leads to the establishment of a pool of latently infected cells. In these cells, mechanisms controlling RNA Polymerase II (RNAPII) pausing and premature transcription termination...
3.
Lista M, Jousset A, Cheng M, SaintAndre V, Perrot E, Rodrigues M, et al.
Retrovirology . 2023 Jul; 20(1):12. PMID: 37434132
No abstract available.
4.
Bonnard D, Le Rouzic E, Singer M, Yu Z, Le Strat F, Batisse C, et al.
Antimicrob Agents Chemother . 2023 Jun; 67(7):e0046223. PMID: 37310224
HIV-1 integrase-LEDGF allosteric inhibitors (INLAIs) share the binding site on the viral protein with the host factor LEDGF/p75. These small molecules act as molecular glues promoting hyper-multimerization of HIV-1 IN...
5.
Lista M, Jousset A, Cheng M, Saint-Andre V, Perrot E, Rodrigues M, et al.
Retrovirology . 2023 May; 20(1):10. PMID: 37254203
Background: Once integrated in the genome of infected cells, HIV-1 provirus is transcribed by the cellular transcription machinery. This process is regulated by both viral and cellular factors, which are...
6.
Konan S, Segeral E, Bejjani F, Bendoumou M, Ait Said M, Gallois-Montbrun S, et al.
Retrovirology . 2022 Feb; 19(1):4. PMID: 35101069
Background: The recent discovery of the role of mA methylation in the regulation of HIV-1 replication unveiled a novel layer of regulation for HIV gene expression. This epitranscriptomic modification of...
7.
Matkovic R, Morel M, Lanciano S, Larrous P, Martin B, Bejjani F, et al.
Nat Commun . 2022 Jan; 13(1):66. PMID: 35013187
The Human Silencing Hub (HUSH) complex constituted of TASOR, MPP8 and Periphilin recruits the histone methyl-transferase SETDB1 to spread H3K9me3 repressive marks across genes and transgenes in an integration site-dependent...
8.
Nguyen Quang N, Goudey S, Segeral E, Mohammad A, Lemoine S, Blugeon C, et al.
Retrovirology . 2020 Aug; 17(1):25. PMID: 32807178
Background: Alternative splicing is a key step in Human Immunodeficiency Virus type 1 (HIV-1) replication that is tightly regulated both temporally and spatially. More than 50 different transcripts can be...
9.
Bonnard D, Le Rouzic E, Eiler S, Amadori C, Orlov I, Bruneau J, et al.
J Biol Chem . 2018 Mar; 293(16):6172-6186. PMID: 29507092
Recently, a new class of HIV-1 integrase (IN) inhibitors with a dual mode of action, called IN-LEDGF/p75 allosteric inhibitors (INLAIs), was described. Designed to interfere with the IN-LEDGF/p75 interaction during...
10.
Amadori C, van der Velden Y, Bonnard D, Orlov I, van Bel N, Le Rouzic E, et al.
Retrovirology . 2017 Nov; 14(1):50. PMID: 29121950
Background: HIV-1 Integrase (IN) interacts with the cellular co-factor LEDGF/p75 and tethers the HIV preintegration complex to the host genome enabling integration. Recently a new class of IN inhibitors was...